A novel mechanism and treatment strategy for age-related macular degeneration

Failure of Autophagy-Lysosomal Pathways in Rod Photoreceptors Causes the Early Retinal Degeneration Phenotype Observed in Cln6(nclf) Mice

Philipp von Eisenhart-Rothe, Alexandra Grubman, Ursula Greferath, Linda J Fothergill, Andrew Jobling, Joanna A Phipps, Anthony R White, Erica L Fletcher, Kirstan A Vessey

2018-10-01

Purpose: Vision loss caused by photoreceptor death represents one of the first symptoms in neuronal ceroid lipofuscinosis, a condi..

Treatment of age related macular degeneration using nanosecond laser therapy: Safety profile studies in humans and mice

Kirstan Anne Vessey, Tracy Ho, Andrew Ian Jobling, Samuel A Mills, Mai Tran, Alice Brandli, Jackson Lam, Robyn H Guymer, Erica L Fletcher

2018-07-01

Prophylactic laser in age-related macular degeneration: the past, the present and the future

Quan Findlay, Andrew I Jobling, Kirstan A Vessey, Ursula Greferath, Joanna A Phipps, Robyn H Guymer, Erica L Fletcher

2018-05-01

The presence of drusen in the posterior eye is a hallmark feature of the early stages of age-related macular degeneration and thei..

Nanosecond Laser Treatment for Age-Related Macular Degeneration Does Not Induce Focal Vision Loss or New Vessel Growth in the Retina

Kirstan A Vessey, Tracy Ho, Andrew I Jobling, Samuel A Mills, Mai X Tran, Alice Brandli, Jackson Lam, Robyn H Guymer, Erica L Fletcher

2018-02-01

Purpose: Subthreshold, nanosecond pulsed laser treatment shows promise as a treatment for age-related macular degeneration (AMD); ..

Reduced Phagocytosis as a novel pathogenic mechanism in AMD pathogenesis

Emily Caruso, Ben Gu, Erica L Fletcher, Xin Huang, Pavan Avula, Kirstan Anne Vessey, James Saville Wiley, Robyn H Guymer

2017-06-01

Evaluation of lipofuscin accumulation and retinal degeneration in the mouse model of the Neuronal Ceroid Lipofuscinosis variant CLN6

Philipp Guennel, Kirstan Vessey, Alexandra Grubman, Anthony White, Erica Fletcher

2016-09-01