Targeting Il-13 Receptor For The Treatment Of Human Asthma

Grant number: 310603


The increasing prevalence and severity of asthma worldwide highlights the need for novel approaches to treat this disease. This proposal will generate antibodies that can be used to specifically block the action of a key molecule known to regulate many of the hallmark features of asthmatic disease. Preclinical evaluation of these antibodies in an established sheep model of human asthma will allow their assessment as a specific therapy for asthma.