Post-Stroke Hyperglycaemia – Treatment With Exenatide in Acute Ischaemic Stroke (Texais) Trial

Abstract

Raised blood glucose levels (hyperglycaemia) after a stroke is common. It reduces the efficacy of stroke treatments and results in worse outcomes. Insulin is not useful as a treatment for this as it causes frequent hypoglycaemia and does not improve clinical outcomes. Exenatide is a common diabetes drug that is simple to use and lowers blood glucose without hypoglycaemia. It will be tested in the Treatment with Exenatide in Acute Ischaemic Stroke (TEXAIS) trial.

Related publications (1)

Management of Poststroke Hyperglycemia: Results of the TEXAIS Randomized Clinical Trial

CF Bladin, N Wah Cheung, HM Dewey, L Churilov, S Middleton, V Thijs, E Ekinci, CR Levi, R Lindley, GA Donnan, MW Parsons, A Meretoja, M Tiainen, PMC Choi, D Cordato, H Brown, BCV Campbell, SM Davis, G Cloud, R Grimley

2023-12-01

BACKGROUND: Hyperglycemia in acute ischemic stroke reduces the efficacy of stroke thrombolysis and thrombectomy, with worse clinic..