CENTRE FOR REDEFINING ANTIBIOTIC USE TO REDUCE RESISTANCE AND PROLONG THE LIVES OF ANTIBIOTICS (REDUCE)

Abstract

Ineffective dosing of antimicrobials has contributed to the escalation of antimicrobial resistance which now pervades the healthcare system. Patients in the intensive care unit and post-transplant are examples of patients who commonly have infections, are more likely to fail treatment and have resistant microbes emerge. In these studies we will characterise the doses of antimicrobials that should be used in these difficult-to-treat patients and rapidly share these for routine clinical use.