DEFINING THE COORDINATION OF IMMUNE RESPONSES TO PATHOGENS
Grant number: 1136550 | Funding period: 2018 - 2022
Understanding how immune responses are coordinated is critical for the design of new therapies and vaccines to target infectious diseases and cancers. This project will utilise advanced imaging combined with novel tools to dissect the complex interactions that occur between immune cells as they are activated and patrol the body to eliminate infectious pathogens.
Related publications (3)
Intravital microscopy of dynamic single-cell behavior in mouse mammary tissue
Caleb A Dawson, Scott N Mueller, Geoffrey J Lindeman, Anne C Rios, Jane E Visvader
Multiphoton intravital imaging is essential for understanding cellular behavior and function in vivo. The adipose-rich environment..
Tissue-resident ductal macrophages survey the mammary epithelium and facilitate tissue remodelling
Caleb A Dawson, Bhupinder Pal, Francois Vaillant, Luke C Gandolfo, Zhaoyuan Liu, Camille Bleriot, Florent Ginhoux, Gordon K Smyth, Geoffrey J Lindeman, Scott N Mueller, Anne C Rios, Jane E Visvader
Macrophages are diverse immune cells that reside in all tissues. Although macrophages have been implicated in mammary-gland functi..