UNDERSTANDING ILLNESS TRAJECTORIES AND DEVELOPING NOVEL THERAPIES FOR INDIVIDUALS WITH PSYCHOSIS

Characteristics and clinical needs of young tertiary students attending a specialist mood disorders clinic.

Kieran M O'Gorman, Lianne Schmaal, Aswin Ratheesh, George Habib, Orania Tokatlidis, Jennifer Jackson-Simpson, Sue M Cotton, Simon M Rice

2023-03-13

OBJECTIVE: To investigate the clinical characteristics of tertiary students and non-students attending a specialist clinic for sev..

Understanding the complexity, patterns, and correlates of alcohol and other substance use among young people seeking help for mental ill-health.

Caroline X Gao, Kate M Filia, Gillinder Bedi, Jana M Menssink, Ellie Brown, Debra J Rickwood, Alexandra G Parker, Sarah E Hetrick, Helen Herrman, Ian Hickie, Nic Telford, Patrick D McGorry, Sue M Cotton

2023-03-13

PURPOSE: Use of alcohol and other substances is a multifaceted issue impacting young people across multiple life domains. This pap..

Childhood trauma and depressive symptoms in bipolar disorder: A network analysis

Anna L Wrobel, Sue M Cotton, Anuradhi Jayasinghe, Claudia Diaz-Byrd, Anastasia K Yocum, Alyna Turner, Olivia M Dean, Samantha E Russell, Elizabeth R Duval, Tobin J Ehrlich, David F Marshall, Michael Berk, Melvin G McInnis

2023-02-07

BACKGROUND: Childhood trauma is related to an increased number of depressive episodes and more severe depressive symptoms in bipol..

A systematic review and meta-analysis of global and social functioning among people at risk of bipolar disorder.

M Watson, K Filia, A Stevens, S Cotton, B Nelson, A Ratheesh

2023-01-15

BACKGROUND: Functional status could predict development of bipolar disorder (BD) or have clinical significance. The relationship b..

Heterogeneity of quality of life in the later stages of first-episode psychosis recovery

EL Clarke, K Allott, JF Anderson, CX Gao, KM Filia, E Killackey, SM Cotton

2022-11-15

PURPOSE: First-episode psychosis (FEP) is characterised by wide heterogeneity in terms of symptom presentation and illness course...

Psychological distress in siblings of people with mental illness: A systematic review and meta-analysis

Anuradhi Jayasinghe, Anna Wrobel, Kate Filia, Linda K Byrne, Glenn Melvin, Lesley Berk, Michael Berk, Sue Cotton

2022-09-16

OBJECTIVE: The objective of this study was to characterise the prevalence and/or severity of psychological distress (namely, depre..

A systematic review comparing caregiver burden and psychological functioning in caregivers of individuals with schizophrenia spectrum disorders and bipolar disorders

George J Karambelas, Kate Filia, Linda K Byrne, Kelly A Allott, Anuradhi Jayasinghe, Sue M Cotton

2022-06-23

BACKGROUND: Informal primary caregivers provide crucial supports to loved ones experiencing serious mental illnesses with profound..

Childhood trauma and treatment outcomes during mood-stabilising treatment with lithium or quetiapine among outpatients with bipolar disorder

Anna L Wrobel, Ole Koehler-Forsberg, Louisa G Sylvia, Samantha E Russell, Olivia M Dean, Sue M Cotton, Michael Thase, Joseph R Calabrese, Thilo Deckersbach, Mauricio Tohen, Charles L Bowden, Melvin G McInnis, James H Kocsis, Edward S Friedman, Terence A Ketter, Richard C Shelton, Michael J Ostacher, Dan Iosifescu, Michael Berk, Alyna Turner

2022-03-11

BACKGROUND: Childhood trauma affects the course of mood disorders. Researchers are now considering childhood trauma as an influent..

Attachment insecurity partially mediates the relationship between childhood trauma and depression severity in bipolar disorder

Anna L Wrobel, Samantha E Russell, Anuradhi Jayasinghe, Mojtaba Lotfaliany, Alyna Turner, Olivia M Dean, Sue M Cotton, Claudia Diaz-Byrd, Anastasia K Yocum, Elizabeth R Duval, Tobin J Ehrlich, David F Marshall, Michael Berk, Melvin G McInnis

2022-03-10

BACKGROUND: Childhood trauma is associated with greater depression severity among individuals with bipolar disorder. However, the ..

The specific phenotype of depression in recent onset schizophrenia spectrum disorders: A symptom profile and network comparison to recent onset major depressive disorder without psychotic features

Sarah E Herniman, Stephen J Wood, Susan M Cotton, Kelly A Allott, Christopher Davey, Michael Berk, Lisa J Phillips

2022-02-01

The specific phenotype of depression in recent-onset schizophrenia spectrum disorders (SSD) and its relation to non-psychotic depr..

Quality of life in first episode psychosis: a cluster analytic approach

Z Liao, K Allott, JF Anderson, E Killackey, SM Cotton

2021-10-18

PURPOSE: Quality of life is increasingly recognised as an important outcome for young people with first episode psychosis (FEP). T..

A comparison of experiences of care and expressed emotion among caregivers of young people with first-episode psychosis or borderline personality disorder features

Sue M Cotton, Jennifer K Betts, Dina Eleftheriadis, Kate Filia, Mirra Seigerman, Victoria K Rayner, Ben McKechnie, Carol Anne Hulbert, Louise McCutcheon, Martina Jovev, Sarah Bendall, Emma Burke, Catharine McNab, Sumudu Mallawaarachchi, Mario Alvarez-Jimenez, Andrew M Chanen, John FM Gleeson

2021-10-11

OBJECTIVE: Caregivers of individuals with severe mental illness often experience significant negative experiences of care, which c..

The influence of childhood trauma on the treatment outcomes of pharmacological and/or psychological interventions for adolescents and adults with bipolar disorder: A systematic review and meta-analysis

Anna L Wrobel, Anuradhi Jayasinghe, Samantha E Russell, Wolfgang Marx, Luis Alameda, Olivia M Dean, Sue M Cotton, Michael Berk, Alyna Turner

2021-10-09

OBJECTIVE: The influence of childhood trauma on the treatment outcomes of pharmacological and/or psychological interventions for a..

Validation of a brief tool to assess and monitor suicidal ideation: The Youth Suicide Ideation Screen (YSIS-3)

Sarah E Hetrick, Caroline X Gao, Kate M Filia, Jana M Menssink, Debra J Rickwood, Helen Herrman, Ian Hickie, Patrick McGorry, Nic Telford, Alexandra G Parker, Sue M Cotton

2021-09-01

BACKGROUND: . Suicidal ideation is common in young people. Assessment and monitoring can help to understand its dynamic nature and..

The psychometric characteristics of the Kessler Psychological Distress Scale (K6) in help-seeking youth: What do you miss when using it as an outcome measure?

SM Cotton, J Menssink, K Filia, D Rickwood, IB Hickie, M Hamilton, S Hetrick, A Parker, H Herrman, PD McGorry, C Gao

2021-08-26

This is the first study to describe psychometric properties of the Kessler Psychological Distress Scale (K6) in a large cohort of ..

A protocol for the first episode psychosis outcome study (FEPOS): >= 15 year follow-up after treatment at the Early Psychosis Prevention and Intervention Centre, Melbourne, Australia

Sue Cotton, Kate Filia, Amity Watson, Andrew J Mackinnon, Leanne Hides, John FM Gleeson, Michael Berk, Philippe Conus, Martin Lambert, Benno Schimmelmann, Helen Herrman, Victoria Rayner, Aswin Ratheesh, Patrick D McGorry

2021-08-20

BACKGROUND: Specialist early intervention (SEI) service models are designed to treat symptoms, promote social and vocational recov..

Severe and complex youth depression: Clinical and historical features of young people attending a tertiary mood disorders clinic

Simon M Rice, Ben McKechnie, Susan Cotton, Abi Brooker, Vita Pilkington, Belinsha Youzchalveen, Lianne Schmaal, Christopher G Davey

2021-06-25

AIM: The concept of severe and complex youth depression has evolved from clinical experience. Here we conducted a file audit study..

Interrelationships between depressive symptoms and positive and negative symptoms of recent onset schizophrenia spectrum disorders: A network analytical approach

Sarah E Herniman, Lisa J Phillips, Stephen J Wood, Sue M Cotton, Edith J Liemburg, Kelly A Allott

2021-06-15

OBJECTIVE: There is a need to better understand the interrelationships between positive and negative symptoms of recent-onset schi..

Characteristics and predictors of suicidality in young people with clinical depression: a systematic review protocol

Carl I Moller, Christopher G Davey, Paul B Badcock, Sue M Cotton

2021-05-01

OBJECTIVE: The objective of this review is to examine clinical, psychosocial, and biological factors associated with suicidality i..

The Role of Instrumental Swallowing Assessment in Adults in Residential Aged Care Homes: A National Modified Delphi Survey Examining Beliefs and Practices

Olga Birchall, Michelle Bennett, Nadine Lawson, Susan M Cotton, Adam P Vogel

2021-04-09

Many adults in residential aged care homes (RACHs) live with oropharyngeal dysphagia (OD) and its physiological, psychosocial, and..

Influence of childhood trauma on the treatment outcomes of pharmacological and/or psychological interventions for adolescents and adults with bipolar disorder: protocol for a systematic review and meta-analysis

Anna Wrobel, Samantha E Russell, Olivia M Dean, Sue Cotton, Michael Berk, Alyna Turner

2021-04-01

INTRODUCTION: Despite available pharmacological and psychological treatments, remission rates for bipolar disorder remain relative..

Trajectories of change in depression symptoms and suicidal ideation over the course of evidence-based treatment for depression: Secondary analysis of a randomised controlled trial of cognitive behavioural therapy plus fluoxetine in young people

Katrina Witt, Trine Madsen, Michael Berk, Olivia Dean, Andrew Chanen, Patrick D McGorry, Sue Cotton, Christopher G Davey, Sarah Hetrick

2021-03-15

OBJECTIVES: Effective treatment of depression is a key target for suicide prevention strategies. However, only around one-third of..

The psychometric validity of the Montgomery-Asberg Depression Rating Scale (MADRS) in recent onset schizophrenia spectrum disorders

Sarah E Herniman, Sue M Cotton, Kelly A Allott, Lisa J Phillips, Stephen J Wood

2021-02-04

Earlier recognition and accurate assessment of depressive symptoms is important to improving outcomes in individuals with recent-o..

Instrumental Swallowing Assessment in Adults in Residential Aged Care Homes: A Scoping Review

Olga Birchall, Michelle Bennett, Nadine Lawson, Susan M Cotton, Adam P Vogel

2021-02-02

OBJECTIVES: To systematically describe evidence on the use of instrumental swallowing assessment for residents of aged care homes...

Relationships Between Different Dimensions of Social Support and Suicidal Ideation in Young People with Major Depressive Disorder

Carl Moller, Sue M Cotton, Paul B Badcock, Sarah E Hetrick, Michael Berk, Olivia M Dean, Andrew M Chanen, Christopher G Davey

2021-01-20

BACKGROUND: Suicidal ideation (SI) is a common feature of depression and is closely associated with suicidal behaviour. Social sup..

Rates, types and associations of sexual risk behaviours and sexually transmitted infections in those with severe mental illness: a scoping review

Meg Stevens, Aswin Ratheesh, Amity Watson, Kate Filia, Brian O Donoghue, Sue M Cotton

2020-08-01

The aim of this scoping review was to: (i) determine rates and types of sexual risk behaviours and sexually-transmitted infections..

Aripiprazole compared with placebo for auditory verbal hallucinations in youth with borderline personality disorder: Protocol for the VERBATIM randomized controlled trial

Andrew M Chanen, Jennifer Betts, Henry Jackson, Patrick McGorry, Barnaby Nelson, Sue M Cotton, Cali Bartholomeusz, Martina Jovev, Aswin Ratheesh, Christopher Davey, Christos Pantelis, Louise McCutcheon, Shona Francey, Amit Bhaduri, Danielle Lowe, Victoria Rayner, Katherine Thompson

2019-12-01

AIM: Up to half of patients with borderline personality disorder report auditory verbal hallucinations that are phenomenologically..

Improving functional outcomes in early-stage bipolar disorder: The protocol for the REsearch into COgnitive and behavioural VERsatility trial

Sue M Cotton, Michael Berk, Henry Jackson, Greg Murray, Kate Filia, Melissa Hasty, Andrew Chanen, Christopher Davey, Barnaby Nelson, Aswin Ratheesh, Craig MacNeil

2019-12-01

AIM: Young people with bipolar disorder (BD) commonly experience reduced quality of life, persistent symptoms and impaired functio..

Sleep problems and anxiety from 2 to 8years and the influence of autistic traits: a longitudinal study

Jacqueline Uren, Amanda L Richdale, Sue M Cotton, Andrew JO Whitehouse

2019-08-01

Whether or not childhood sleep problems and anxiety occur simultaneously, or one precedes the other, and any effect of autistic tr..

HORYZONS trial: protocol for a randomised controlled trial of a moderated online social therapy to maintain treatment effects from first-episode psychosis services

Mario Alvarez-Jimenez, Sarah Bendall, Peter Koval, Simon Rice, Daniela Cagliarini, Lee Valentine, Simon D'Alfonso, Christopher Miles, Penni Russon, David L Penn, Jess Phillips, Reeva Lederman, Greg Wadley, Eoin Killackey, Olga Santesteban-Echarri, Cathrine Mihalopoulos, Helen Herrman, Cesar Gonzalez-Blanch, Tamsyn Gilbertson, Shalini Lal

2019-06-01

INTRODUCTION: Specialised early intervention services have demonstrated improved outcomes in first-episode psychosis (FEP); howeve..

Protocol and Rationale: A 24-week Double-blind, Randomized, Placebo Controlled Trial of the Efficacy of Adjunctive Garcinia mangostana Linn. (Mangosteen) Pericarp for Schizophrenia

Alyna Turner, John J McGrath, Olivia M Dean, Seetal Dodd, Andrea Baker, Susan M Cotton, James G Scott, Bianca E Kavanagh, Melanie M Ashton, Adam J Walker, Ellie Brown, Michael Berk

2019-05-01

OBJECTIVE: : Garcinia mangostana Linn., commonly known as mangosteen, is a tropical fruit with a thick pericarp rind containing bi..