UNDERSTANDING AND EFFECTIVELY TREATING COGNITIVE AND FUNCTIONING IMPAIRMENTS IN YOUTH WITH PSYCHOSIS AND OTHER MENTAL DISORDERS

Increased cortical surface area but not altered cortical thickness or gyrification in bipolar disorder following stabilisation from a first episode of mania

Tamsyn E Van Rheenen, Sue M Cotton, Orwa Dandash, Rebecca E Cooper, Elysha Ringin, Rothanthi Daglas-Georgiou, Kelly Allott, Yann Chye, Chao Suo, Craig Macneil, Melissa Hasty, Karen Hallam, Patrick McGorry, Alex Fornito, Murat Yucel, Christos Pantelis, Michael Berk

2023-03-02

BACKGROUND: Despite reports of altered brain morphology in established bipolar disorder (BD), there is limited understanding of wh..

Heterogeneity of quality of life in the later stages of first-episode psychosis recovery

EL Clarke, K Allott, JF Anderson, CX Gao, KM Filia, E Killackey, SM Cotton

2022-11-15

PURPOSE: First-episode psychosis (FEP) is characterised by wide heterogeneity in terms of symptom presentation and illness course...

Effects of omega-3 polyunsaturated fatty acid supplementation on cognitive functioning in youth at ultra-high risk for psychosis: secondary analysis of the NEURAPRO randomised controlled trial

Nicholas Cheng, Alison McLaverty, Barnaby Nelson, Connie Markulev, Miriam R Schafer, Maximus Berger, Nilufar Mossaheb, Monika Schlogelhofer, Stefan Smesny, Ian B Hicikie, Gregor E Berger, Eric YH Chen, Lieuwe de Haan, Dorien H Nieman, Merete Nordentoft, Anita Riecher-Rossler, Swapna Verma, Rebekah Street, Andrew Thompson, Hok Pan Yuen

2022-09-08

BACKGROUND: Cognitive impairments are well-established features of psychotic disorders and are present when individuals are at ult..

Intelligence trajectories in individuals at ultra-high risk for psychosis: An 8-year longitudinal analysis

Nicholas Cheng, Ashleigh Lin, Stephen Bowden, Caroline Gao, Alison R Yung, Barnaby Nelson, Andrew Thompson, Hok Pan Yuen, Warrick J Brewer, Daniela Cagliarini, Annie Bruxner, Magenta Simmons, Christina Broussard, Christos Pantelis, Patrick D McGorry, Kelly Allott, Stephen J Wood

2022-08-30

Cognitive impairment is a well-documented predictor of transition to a full-threshold psychotic disorder amongst individuals at ul..

A systematic review comparing caregiver burden and psychological functioning in caregivers of individuals with schizophrenia spectrum disorders and bipolar disorders

George J Karambelas, Kate Filia, Linda K Byrne, Kelly A Allott, Anuradhi Jayasinghe, Sue M Cotton

2022-06-23

BACKGROUND: Informal primary caregivers provide crucial supports to loved ones experiencing serious mental illnesses with profound..

Cognitive Strengths in First-Episode Psychosis: Perspectives of Cognition Experts

S Bryce, F Boyer, LJ Phillips, EM Parrish, M Alvarez-Jimenez, K Allott

2022-06-01

Cognitive impairments are core features of first-episode psychosis (FEP). A cognitive strengths based approach to treatment in FEP..

Cognitive strengths in first-episode psychosis: perspectives from young people with lived experience

Shayden Bryce, Ashleigh de Winter, Lisa Phillips, Nicholas Cheng, Mario Alvarez-Jimenez, Kelly Allott

2022-03-25

Background: Identifying cognitive strengths may be one avenue for enhancing functional recovery in people with first-episode psych..

Decisional capacity in young people with first episode psychosis, major depressive disorder and no mental disorder

Kelly Allott, Sarah Whitson, Shona M Francey, Christina Bryant, Magenta B Simmons, Chiara MJ Killey

2022-02-17

We aimed to (1) examine decisional capacity for treatment in young people (aged 15 to 25 years) with first-episode psychosis (FEP)..

The specific phenotype of depression in recent onset schizophrenia spectrum disorders: A symptom profile and network comparison to recent onset major depressive disorder without psychotic features

Sarah E Herniman, Stephen J Wood, Susan M Cotton, Kelly A Allott, Christopher Davey, Michael Berk, Lisa J Phillips

2022-02-01

The specific phenotype of depression in recent-onset schizophrenia spectrum disorders (SSD) and its relation to non-psychotic depr..

Twelve-Month Cognitive Trajectories in Individuals at Ultra-High Risk for Psychosis: A Latent Class Analysis

K Allott, SJ Schmidt, HP Yuen, SJ Wood, B Nelson, C Markulev, S Lavoie, WJ Brewer, MR Schäfer, N Mossaheb, M Schlögelhofer, S Smesny, IB Hickie, GE Berger, EYH Chen, L De Haan, DH Nieman, M Nordentoft, A Riecher-Rössler, S Verma

2022-01-01

Understanding longitudinal cognitive performance in individuals at ultra-high risk for psychosis (UHR) is important for informing ..

Cognitive strengths in first episode psychosis: a thematic analysis of clinicians' perspectives

Peter Steele, Nicholas Cheng, Lisa J Phillips, Shayden Bryce, Mario Alvarez-Jimenez, Kelly Allott

2021-12-08

BACKGROUND: Cognitive deficits are associated with poor functional outcomes in individuals recovering from a first episode of psyc..

Treatments for objective and subjective cognitive functioning in young people with depression: Systematic review of current evidence

Rothanthi Daglas-Georgiou, Shayden Bryce, Gabriel Smith, Manreena Kaur, Nicholas Cheng, Magdalene De Rozario, Stephen J Wood, Kelly Allott

2021-11-25

AIM: Cognitive deficits are recognized features of depressive disorders in youth aged 12-25. These deficits are distressing, predi..

Quality of life in first episode psychosis: a cluster analytic approach

Z Liao, K Allott, JF Anderson, E Killackey, SM Cotton

2021-10-18

PURPOSE: Quality of life is increasingly recognised as an important outcome for young people with first episode psychosis (FEP). T..

Cognitive remediation to address impairment in schizophrenia: Moving beyond effectiveness and toward implementation

Shayden Bryce, Isabel Zbukvic, J Stephen Wood, Kelly Allott

2021-10-11

Interrelationships between depressive symptoms and positive and negative symptoms of recent onset schizophrenia spectrum disorders: A network analytical approach

Sarah E Herniman, Lisa J Phillips, Stephen J Wood, Sue M Cotton, Edith J Liemburg, Kelly A Allott

2021-06-15

OBJECTIVE: There is a need to better understand the interrelationships between positive and negative symptoms of recent-onset schi..

The Neuropsychological Symptoms Self-Report: psychometric properties in an adolescent and young adult mental health cohort

Kelly Allott, Caroline X Gao, Caroline Fisher, Sarah E Hetrick, Kate M Filia, Jana M Menssink, Helen E Herrman, Debra J Rickwood, Alexandra G Parker, Patrick D McGorry, Sue M Cotton

2021-04-29

BACKGROUND: Subjective cognitive symptoms are common in young people receiving mental health treatment and are associated with poo..

Mental images of suicide: Theoretical framework and preliminary findings in depressed youth attending outpatient care.

MR De Rozario, LS Van Velzen, P Davies, SM Rice, CG Davey, J Robinson, M Alvarez-Jimenez, K Allott, B McKechnie, KL Felmingham, L Schmaal

2021-04-01

Cognitive ability and metabolic physical health in first-episode psychosis

Sarah Whitson, Brian O'Donoghue, Robert Hester, Lara Baldwin, Susy Harrigan, Shona Francey, Jessica Graham, Barnaby Nelson, Aswin Ratheesh, Mario Alvarez-Jimenez, Alex Fornito, Christos Pantelis, Hok Pan Yuen, Andrew Thompson, Melissa Kerr, Michael Berk, Stephen J Wood, Patrick McGorry, Kelly Allott

2021-02-13

Cognitive impairments are a core feature of first-episode psychosis (FEP), arising before illness onset and antipsychotic exposure..

The psychometric validity of the Montgomery-Asberg Depression Rating Scale (MADRS) in recent onset schizophrenia spectrum disorders

Sarah E Herniman, Sue M Cotton, Kelly A Allott, Lisa J Phillips, Stephen J Wood

2021-02-04

Earlier recognition and accurate assessment of depressive symptoms is important to improving outcomes in individuals with recent-o..

Distinguishing schizophrenia spectrum from non-spectrum disorders among young patients with first episode psychosis and at high clinical risk: The role of basic self-disturbance and neurocognition

Jessica Spark, Lukasz Gaweda, Kelly Allott, Jessica A Hartmann, Bradley N Jack, Dan Koren, Suzie Lavoie, Emily Li, Patrick D McGorry, Josef Parnas, Andrea Polari, Louis A Sass, Thomas Whitford, Barnaby Nelson

2021-01-09

INTRODUCTION: The distinction between the schizophrenia spectrum and other types of disorders may be clinically relevant in terms ..

Subjective cognitive functioning in relation to changes in levels of depression and anxiety in youth over 3 months of treatment

Kelly Allott, Caroline Gao, Sarah E Hetrick, Kate M Filia, Jana M Menssink, Caroline Fisher, Ian B Hickie, Helen E Herrman, Debra J Rickwood, Alexandra G Parker, Patrick D Mcgorry, Sue M Cotton

2020-09-01

BACKGROUND: Subjective cognitive difficulties are common in mental illness and have a negative impact on role functioning. Little ..

Cognitive strengths-based assessment and intervention in first-episode psychosis: A complementary approach to addressing functional recovery?

Kelly Allott, Peter Steele, Frances Boyer, Ashleigh de Winter, Shayden Bryce, Mario Alvarez-Jimenez, Lisa Phillips

2020-07-01

People who have experienced psychosis describe functional and personal recovery as a key goal of treatment. To date, the early, pe..

Compensatory Interventions for Cognitive Impairments in Psychosis: A Systematic Review and Meta-Analysis

Kelly Allott, Kristi Van-der-EL, Shayden Bryce, Emma M Parrish, Susan R McGurk, Sarah Hetrick, Christopher R Bowie, Sean Kidd, Matthew Hamilton, Eoin Killackey, Dawn Velligan

2020-07-01

OBJECTIVE: Cognitive compensatory interventions aim to alleviate psychosocial disability by targeting functioning directly using a..

INdividual Vocational and Educational Support Trial (INVEST) for young people with borderline personality disorder: study protocol for a randomised controlled trial

Andrew M Chanen, Katie Nicol, Jennifer K Betts, Gary R Bond, Cathrine Mihalopoulos, Henry J Jackson, Katherine N Thompson, Martina Jovev, Hok Pan Yuen, Gina Chinnery, Judith Ring, Kelly Allott, Louise McCutcheon, Ashleigh P Salmon, Eoin Killackey

2020-06-26

Background: The clinical onset of borderline personality disorder (BPD) usually occurs in young people (aged 12–25 years) and comm..

The complexities of understanding cognitive trajectory in bipolar disorder

Kelly Allott, Tamsyn E Van Rheenen

2020-04-20

Cognitive functioning in ultra -high risk for psychosis individuals with and without depression: Secondary analysis of findings from the NEURAPRO randomized clinical trial

Sumudu Rasangi Mallawaarachchi, G Paul Amminger, John Farhall, Luke K Bolt, Barnaby Nelson, Hok Pan Yuen, Patrick D McGorry, Connie Markulev, Miriam R Schaefer, Nilufar Mossaheb, Monika Schloegelhofer, Stefan Smesny, Ian B Hickie, Gregor Emanuel Berger, Eric YH Chen, Lieuwe de Haan, Dorien H Nieman, Merete Nordentoft, Anita Riecher-Roessler, Swapna Verma

2020-04-01

Neurocognitive impairments are well established in both ultra-high risk (UHR) for psychosis and major depressive disorder (MDD). D..

Youth access clinics in Gippsland: Barriers and enablers to service accessibility in rural settings

Erin Dolan, Kelly Allott, Amanda Proposch, Matthew Hamilton, Eoin Killackey

2020-02-13

AIM: Approximately 15 years ago, four youth access clinics (YACs) were established in the Gippsland region to improve mental and g..

Acceptability, safety and perceived impact of providing a fact sheet to young people about cognitive symptoms in depression

Shayden Bryce, Melanie Cooke, Hok Pan Yuen, Kelly Allott

2020-02-11

AIM: Cognitive deficits are common in young people, aged 15-25, with depression. Nevertheless, these symptoms are not routinely ad..

Harmonised collection of data in youth mental health: Towards large datasets

Suzie Lavoie, Kelly Allott, Paul Amminger, Cali Bartholomeusz, Maximus Berger, Michael Breakspear, Anjali K Henders, Rico Lee, Ashleigh Lin, Patrick McGorry, Simon Rice, Lianne Schmaal, Stephen J Wood

2020-01-01

OBJECTIVE: The current international trend is to create large datasets with existing data and/or deposit newly collected data into..

Depressive psychopathology in first-episode schizophrenia spectrum disorders: a systematic review, meta-analysis and meta-regression

Sarah E Herniman, Kelly Allott, Lisa J Phillips, Stephen J Wood, Jacqueline Uren, Sumudu R Mallawaarachchi, Sue M Cotton

2019-11-01

BACKGROUND: Despite knowing for many decades that depressive psychopathology is common in first-episode schizophrenia spectrum dis..

The efficacy and safety of nutrient supplements in the treatment of mental disorders: a meta-review of meta-analyses of randomized controlled trials

Joseph Firth, Scott B Teasdale, Kelly Allott, Dan Siskind, Wolfgang Marx, Jack Cotter, Nicola Veronese, Felipe Schuch, Lee Smith, Marco Solmi, Andre F Carvalho, Davy Vancampfort, Michael Berk, Brendon Stubbs, Jerome Sarris

2019-10-01

The role of nutrition in mental health is becoming increasingly acknowledged. Along with dietary intake, nutrition can also be obt..

Thematic analysis of youth mental health providers' perceptions of neuropsychological assessment services

Garance Delagneau, Stephen C Bowden, Shayden Bryce, Kristi van-der-EL, Matthew Hamilton, Sophie Adams, Liz Burgat, Eoin Killackey, Debra Rickwood, Kelly Allott

2019-09-11

AIM: A growing number of quantitative studies have investigated the utility of neuropsychological assessment in mental health sett..

Longitudinal Cognitive Performance in Individuals at Ultrahigh Risk for Psychosis: A 10-year Follow-up

Kelly Allott, Stephen J Wood, Hok Pan Yuen, Alison R Yung, Barnaby Nelson, Warrick J Brewer, Daniela Spiliotacopoulos, Annie Bruxner, Magenta Simmons, Christina Broussard, Sumudu Mallawaarachchi, Christos Pantelis, Patrick D McGorry, Ashleigh Lin

2019-09-01

It remains unclear whether the onset of psychosis is associated with deterioration in cognitive performance. The aim of this study..

Cognitive screening: A significant unmet need in youth mental health

Shayden Bryce, Kelly Allott

2019-08-01

Subjective experiences of neurocognitive functioning in young people with major depression

Catherine Morey-Nase, Lisa J Phillips, Shayden Bryce, Sarah Hetrick, Andrea L Wright, Emma Caruana, Kelly Allott

2019-07-04

BACKGROUND: Research suggests that young people with major depressive disorder (MDD) experience neurocognitive deficits and that t..

The Vitamins in Psychosis Study: A Randomized, Double-Blind, Placebo-Controlled Trial of the Effects of Vitamins B-12, B-6, and Folic Acid on Symptoms and Neurocognition in First-Episode Psychosis

Kelly Allott, Patrick D McGorry, Hok Pan Yuen, Joseph Firth, Tina-Marie Proffitt, Gregor Berger, Paul Maruff, Michaels K O'Regan, Alicia Papas, Timothy CB Stephens, Colin P O'Donnell

2019-07-01

BACKGROUND: Elevated homocysteine is observed in schizophrenia and associated with illness severity. The aim of this study was to ..