IMPORTANCE OF FUNCTIONAL ANTIBODIES AGAINST INFECTIOUS DISEASES

Abstract

Antibodies are highly functional proteins capable of recognizing infectious disease pathogens and instructing surrounding immune cells to attack them. This project aims to identify specific antibody targets on HIV and Mycobacterium Tuberculosis associated with protection/control of disease and to understand the mechanisms behind the most functional antibodies. Ultimately, these studies will guide the development of future vaccines and therapies against these deadly pathogens.