TARGETING RIBOSOME SYNTHESIS AND FUNCTION TO TREAT ADVANCED PROSTATE CANCER

mTOR-mediated podocyte hypertrophy regulates glomerular integrity in mice and humans

Victor G Puelles, James W van der Wolde, Nicola Wanner, Markus W Scheppach, Luise A Cullen-McEwen, Tillmann Bork, Maja T Lindenmeyer, Lukas Gernhold, Milagros N Wong, Fabian Braun, Clemens D Cohen, Michelle M Kett, Christoph Kuppe, Rafael Kramann, Turgay Saritas, Claudia R van Roeyen, Marcus J Moeller, Leon Tribolet, Richard Rebello, Yu BY Sun

2019-09-19

The cellular origins of glomerulosclerosis involve activation of parietal epithelial cells (PECs) and progressive podocyte depleti..

Generally applicable transcriptome-wide analysis of translation using anota2seq

Christian Oertlin, Julie Lorent, Carl Murie, Luc Furic, Ivan Topisirovic, Ola Larsson

2019-07-09

mRNA translation plays an evolutionarily conserved role in homeostasis and when dysregulated contributes to various disorders incl..

Epididymal cysteine-rich secretory proteins are required for epididymal sperm maturation and optimal sperm function

Jinghua Hu, D Jo Merriner, Anne E O'Connor, Brendan J Houston, Luc Furic, Mark P Hedger, Moira K O'Bryan

2018-03-01

STUDY QUESTION: What is the role of epididymal cysteine-rich secretory proteins (CRISPs) in male fertility? SUMMARY ANSWER: While ..