EFFECTS OF TESTOSTERONE AND OESTROGEN ON BODY COMPOSITION
Grant number: 1143333 | Funding period: 2018 - 2021
Masculinising and feminising hormones such as testosterone and oestrogen respectively are important hormones controlling the amount of muscle, fat and bone in the body. By studying people with conditions such as prostate cancer where these hormone levels are disrupted, we aim to understand how testosterone and oestrogen affects various body systems, which may lead to new treatments for important public health problems of frailty, obesity and heart disease, and osteoporosis.
Related publications (24)
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Matthew I Balcerek, Brendan J Nolan, Adam Brownhill, Peggy Wong, Peter Locke, Jeffrey D Zajac, Ada S Cheung
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The Informed Consent Model of Care for Accessing Gender-Affirming Hormone Therapy Is Associated With High Patient Satisfaction
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Ada S Cheung, Rudolf Hoermann, Jasmine Zhu, Daryl Lim Joon, Jeffrey D Zajac, Mathis Grossmann
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Differing Effects of Zoledronic Acid on Bone Microarchitecture and Bone Mineral Density in Men Receiving Androgen Deprivation Therapy: A Randomized Controlled Trial
Ada S Cheung, Rudolf Hoermann, Ali Ghasem-Zadeh, Alistair J Tinson, Vivian Ly, Stefan Milevski, Daryl Lim Joon, Jeffrey D Zajac, Ego Seeman, Mathis Grossmann
Androgen deprivation therapy (ADT) given to men with prostate cancer causes rapid and severe sex steroid deficiency, leading to in..
Global Coagulation Assays in Transgender Women on Oral and Transdermal Estradiol Therapy
Hui Yin Lim, Shalem Y Leemaqz, Niloufar Torkamani, Mathis Grossmann, Jeffrey D Zajac, Harshal Nandurkar, Prahlad Ho, Ada S Cheung
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Testosterone therapy considerations in oestrogen, progesterone and androgen receptor-positive breast cancer in a transgender man
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A 44-year-old premenopausal individual assigned female at birth but with a male gender identity, presented requesting masculinizin..
Sustained remission of Lynch syndrome-associated metastatic adrenocortical carcinoma following checkpoint inhibitor therapy-associated multiorgan autoimmunity
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Non-Binary and Binary Gender Identity in Australian Trans and Gender Diverse Individuals
Ada S Cheung, Shalem Y Leemaqz, John WP Wong, Denise Chew, Olivia Ooi, Pauline Cundill, Nicholas Silberstein, Peter Locke, Sav Zwickl, Ren Grayson, Jeffrey D Zajac, Ken C Pang
Many trans and gender diverse (TGD) people have gender identities that are not exclusively male or female but instead fall in-betw..
Prevalence of Autism Spectrum Disorder and Attention-Deficit Hyperactivity Disorder Amongst Individuals with Gender Dysphoria: A Systematic Review
Emily Thrower, Ingrid Bretherton, Ken C Pang, Jeffrey D Zajac, Ada S Cheung
Autism spectrum disorders (ASD) and attention-deficit hyperactivity disorder (ADHD) can compromise health and may be more prevalen..
Australian endocrinologists need more training in transgender health: A national survey
Ingrid Bretherton, Mathis Grossmann, Shalem Y Leemaqz, Jeffrey D Zajac, Ada S Cheung
OBJECTIVE: An increasing number of trans and gender diverse (TGD) individuals are seeking gender-affirming hormone therapy for gen..
Health Needs of Trans and Gender Diverse Adults in Australia: A Qualitative Analysis of a National Community Survey
Sav Zwickl, Alex Wong, Ingrid Bretherton, Max Rainier, Daria Chetcuti, Jeffrey D Zajac, Ada S Cheung
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Position statement on the hormonal management of adult transgender and gender diverse individuals
Ada S Cheung, Katie Wynne, Jaco Erasmus, Sally Murray, Jeffrey D Zajac
INTRODUCTION: Rising demand for gender-affirming hormone therapy mandates a need for more formalised care of transgender and gende..
Biomechanical leg muscle function during stair ambulation in men receiving androgen deprivation therapy.
Ada S Cheung, Hans A Gray, Anthony G Schache, Rudolf Hoermann, Jarrod Bicknell, Daryl Lim Joon, Jeffrey D Zajac, Marcus G Pandy, Mathis Grossmann
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Cyproterone acetate or spironolactone in lowering testosterone concentrations for transgender individuals receiving oestradiol therapy
Lachlan Angus, Shalem Leemaqz, Olivia Ooi, Pauline Cundill, Nicholas Silberstein, Peter Locke, Jeffrey D Zajac, Ada S Cheung
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Selective Loss of Levator Ani and Leg Muscle Volumes in Men Undergoing Androgen Deprivation Therapy
Ada S Cheung, Christopher Cunningham, Dong-Kyoon Daniel Ko, Vivian Ly, Hans Gray, Rudolf Hoermann, Boyd JG Strauss, Ebrahim Bani Hassan, Gustavo Duque, Peter Ebeling, Marcus G Pandy, Jeffrey D Zajac, Mathis Grossmann
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Cross-sex hormone therapy in Australia: the prescription patterns of clinicians experienced in adult transgender healthcare
Ingrid Bretherton, Emily Thrower, Mathis Grossmann, Jeffrey D Zajac, Ada S Cheung
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Gender-affirming hormone therapy and the risk of sex hormone-dependent tumours in transgender individuals-A systematic review
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Sociodemographic and Clinical Characteristics of Transgender Adults in Australia.
Ada S Cheung, Olivia Ooi, Shalem Leemaqz, Pauline Cundill, Nicholas Silberstein, Ingrid Bretherton, Emily Thrower, Peter Locke, Mathis Grossmann, Jeffrey D Zajac
Background: Over the last 10 years, increases in demand for transgender health care has occurred worldwide. There are few data on ..