CHEMO-PREVENTION OF TROPICAL CANINE PARASITOSES AND VECTOR-BORNE DISEASES

Grant number: LP170100187 | Funding period: 2018 - 2021

Completed

Abstract

This project will determine the prevalence and diversity of established, emerging and novel canine vector-borne agents and endoparasites in a tropical setting by using conventional and next generation molecular diagnostic tools. It will fill an important gap by providing independently-verified evidence on how well canine anti-parasitic products marketed in Australia and Asia by Bayer Animal Health, perform in high-infection pressure settings, as a chemo-preventative for these disease agents. Tropical regions spanning northern Australia and Southern Asia are highly conducive to a plethora of canine vector-borne and parasitic pathogens that cause significant morbidity and mortality in dogs. Ma..

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Related publications (8)

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Advanced approaches for the diagnosis and chemoprevention of canine vector-borne pathogens and parasites—Implications for the Asia-Pacific region and beyond

LG Huggins, AV Koehler, RB Gasser, RJ Traub

2023-01-01

Vector-borne pathogens (VBPs) of canines are a diverse range of infectious agents, including viruses, bacteria, protozoa and multi..

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Field trial investigating the efficacy of a long-acting imidacloprid 10%/flumethrin 4.5% polymer matrix collar (Seresto®, Elanco) compared to monthly topical fipronil for the chemoprevention of canine tick-borne pathogens in Cambodia.

Lucas G Huggins, Mark Stevenson, Zahida Baydoun, Ron Mab, Yulia Khouri, Bettina Schunack, Rebecca J Traub

2022-01-01

The tropical brown dog tick, Rhipicephalus linnaei, commonly infests canines in the tropics and is an important vector for disease..

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Zoonotic hookworms of dogs and cats-lessons from the past to inform current knowledge and future directions of research

Rebecca J Traub, Patsy A Zendejas-Heredia, Luca Massetti, Vito Colella

2021-12-15

The early-to-mid 1900s was an era that marked the first published reports of clinical cases and experimental human infections that..

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A multipronged next-generation sequencing metabarcoding approach unearths hyper-diverse and abundant dog pathogen communities in Cambodia

Lucas G Huggins, Vito Colella, Anson V Koehler, Bettina Schunack, Rebecca J Traub

2021-06-07

Recent surveys in Southeast Asia, including Cambodia, have identified canine vector-borne pathogens (VBPs), including those with z..

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Novel High-Throughput Multiplex qPCRs for the Detection of Canine Vector-Borne Pathogens in the Asia-Pacific

Lucas Huggins, Luca Massetti, Bettina Schunack, Vito Colella, Rebecca Traub

2021-05-01

The Asia-Pacific hosts a large diversity of canine vector-borne pathogens (VBPs) with some of the most common and most pathogenic,..

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A Host-Specific Blocking Primer Combined with Optimal DNA Extraction Improves the Detection Capability of a Metabarcoding Protocol for Canine Vector-Borne Bacteria

Lucas G Huggins, Anson Koehler, Bettina Schunack, Tawin Inpankaew, Rebecca J Traub

2020-04-01

Bacterial canine vector-borne diseases are responsible for some of the most life-threatening conditions of dogs in the tropics and..

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A novel metabarcoding diagnostic tool to explore protozoan haemoparasite diversity in mammals: a proof-of-concept study using canines from the tropics

Lucas G Huggins, Anson Koehler, Ng-Nguyen Dinh, Stephen Wilcox, Bettina Schunack, Tawin Inpankaew, Rebecca J Traub

2019-09-02

Haemoparasites are responsible for some of the most prevalent and debilitating canine illnesses across the globe, whilst also posi..

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Assessment of a metabarcoding approach for the characterisation of vector-borne bacteria in canines from Bangkok, Thailand

Lucas G Huggins, Anson Koehler, Ng-Nguyen Dinh, Stephen Wilcox, Bettina Schunack, Tawin Inpankaew, Rebecca J Traub

2019-08-08

BACKGROUND: Globally, bacterial vector-borne disease (VBD) exerts a large toll on dogs in terms of morbidity and mortality but now..