No pain no word gain: toward a new neurobiological account of word learning

Grant number: DE180100893 | Funding period: 2018 - 2021

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Abstract

This project aims to generate a novel neurobiological account of word learning, going beyond a simple mapping between words and objects and recognising the sensory and socio-communicative embedding of language. Capitalising on interdisciplinary approaches to research, this project will use state-of-the-art neuroimaging to reveal the neural architecture and mechanisms supporting contextualised sensory word learning. The results are expected to bring about a paradigm shift in the fields of neurobiology of language and learning, having a profound impact on the practice of language teaching and improvement of language functioning.

Related publications (14)

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Dynamic Regional Brain Atrophy Rates in the First Year After Ischemic Stroke

Amy Brodtmann, Mohamed Salah Khlif, Natalia Egorova, Michele Veldsman, Laura J Bird, Emilio Werden

2020-09-01

BACKGROUND AND PURPOSE: Brain atrophy can be regarded as an end-organ effect of cumulative cardiovascular risk factors. Accelerate..

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Regional neurodegeneration correlates with sleep-wake dysfunction after stroke

Elie Gottlieb, Natalia Egorova, Mohamed S Khlif, Wasim Khan, Emilio Werden, Matthew P Pase, Mark Howard, Amy Brodtmann

2020-09-01

Sleep-wake disruption is a key modifiable risk factor and sequela of stroke. The pathogenesis of poststroke sleep dysfunction is u..

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Three-tissue compositional analysis reveals in-vivo microstructural heterogeneity of white matter hyperintensities following stroke

Wasim Khan, Natalia Egorova, Mohamed Salah Khlif, Remika Mito, Thijs Dhollander, Amy Brodtmann

2020-09-01

White matter hyperintensities (WMHs) are frequently observed on brain scans of older individuals and are associated with cognitive..

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Pervasive White Matter Fiber Degeneration in Ischemic Stroke

Natalia Egorova, Thijs Dhollander, Mohamed Salah Khlif, Wasim Khan, Emilio Werden, Amy Brodtmann

2020-05-01

Background and Purpose- We examined if ischemic stroke is associated with white matter degeneration predominantly confined to the ..

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Microstructural degeneration underlies executive dysfunction after stroke

Michele Veldsman, Emilio Werden, Natalia Egorova, Mohamed Salah Khlif, Amy Brodtmann

2020-02-04

<h4>ABSTRACT</h4> <h4>Objective</h4> Executive dysfunction affects 40% of stroke patients and is associated with poor quality of l..

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Between placebo and nocebo: Response to control treatment is mediated by amygdala activity and connectivity

Natalia Egorova, Fabrizio Benedetti, Randy L Gollub, Jian Kong

2019-12-12

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Predicted Brain Age After Stroke

Natalia Egorova, Franziskus Liem, Vladimir Hachinski, Amy Brodtmann

2019-12-10

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Choroid plexus volume after stroke

Natalia Egorova, Elie Gottlieb, Mohamed Salah Khlif, Neil J Spratt, Amy Brodtmann

2019-12-01

BACKGROUND: Cerebrospinal fluid circulation is crucial for the functioning of the brain. Aging and brain pathologies such as Alzhe..

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A Human Depression Circuit Derived From Focal Brain Lesions

Jaya L Padmanabhan, Danielle Cooke, Juho Joutsa, Shan H Siddiqi, Michael Ferguson, R Ryan Darby, Louis Soussand, Andreas Horn, Na Young Kim, Joel L Voss, Andrew M Naidech, Amy Brodtmann, Natalia Egorova, Sophia Gozzi, Thanh G Phan, Maurizio Corbetta, Jordan Grafman, Michael D Fox

2019-11-15

BACKGROUND: Focal brain lesions can lend insight into the causal neuroanatomical substrate of depression in the human brain. Howev..

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A comparison of automated segmentation and manual tracing in estimating hippocampal volume in ischemic stroke and healthy control participants

Mohamed Salah Khlif, Natalia Egorova, Emilio Werden, Alberto Redolfi, Marina Boccardi, Charles S DeCarli, Evan Fletcher, Baljeet Singh, Qi Li, Laura Bird, Amy Brodtmann

2019-01-01

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A neural mechanism of direct and observational conditioning for placebo and nocebo responses

Yiheng Tu, Joel Park, Seppo P Ahlfors, Sheraz Khan, Natalia Egorova, Courtney Lang, Jin Cao, Jian Kong

2019-01-01

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APOE epsilon 4 Carriers Show Delayed Recovery of Verbal Memory and Smaller Entorhinal Volume in the First Year After Ischemic Stroke

Emilio Werden, Mohamed Salah Khlif, Laura J Bird, Toby Cumming, Jennifer Bradshaw, Wasim Khan, Matthew Pase, Carolina Restrepo, Michele Veldsman, Natalia Egorova, Sheila K Patel, Elie Gottlieb, Amy Brodtmann

2019-01-01

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Assessment of longitudinal hippocampal atrophy in the first year after ischemic stroke using automatic segmentation techniques

Mohamed Salah Khlif, Emilio Werden, Natalia Egorova, Marina Boccardi, Alberto Redolfi, Laura Bird, Amy Brodtmann

2019-01-01

We assessed first-year hippocampal atrophy in stroke patients and healthy controls using manual and automated segmentations: AdaBo..

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In the face of pain: The choice of visual cues in pain conditioning matters

N Egorova, J Park, J Kong

2017-08-01