No pain no word gain: toward a new neurobiological account of word learning

Atrophy of Ipsilesional Hippocampal Subfields Vary Over First Year After Ischemic Stroke.

Mohamed Salah Khlif, Emilio Werden, Laura J Bird, Natalia Egorova-Brumley, Amy Brodtmann

2021-11-27

BACKGROUND: The structural integrity of hippocampal subfields has been investigated in many neurological disorders and was shown t..

Fixel-based Analysis of Diffusion MRI: Methods, Applications, Challenges and Opportunities

Thijs Dhollander, Adam Clemente, Mervyn Singh, Frederique Boonstra, Oren Civier, Juan Dominguez Duque, Natalia Egorova, Peter Enticott, Ian Fuelscher, Sanuji Gajamange, Sila Genc, Elie Gottlieb, Christian Hyde, Phoebe Imms, Claire Kelly, Melissa Kirkovski, Scott Kolbe, Xiaoyun Liang, Atul Malhotra, Remika Mito

2021-11-01

Diffusion MRI has provided the neuroimaging community with a powerful tool to acquire in-vivo data sensitive to microstructural fe..

Sleep architectural dysfunction and undiagnosed obstructive sleep apnea after chronic ischemic stroke

Elie Gottlieb, Mohamed S Khlif, Laura Bird, Emilio Werden, Thomas Churchward, Matthew P Pase, Natalia Egorova, Mark E Howard, Amy Brodtmann

2021-07-01

OBJECTIVE/BACKGROUND: Sleep-wake dysfunction is bidirectionally associated with the incidence and evolution of acute stroke. It re..

Dynamic Regional Brain Atrophy Rates in the First Year After Ischemic Stroke

Amy Brodtmann, Mohamed Salah Khlif, Natalia Egorova, Michele Veldsman, Laura J Bird, Emilio Werden

2020-09-01

BACKGROUND AND PURPOSE: Brain atrophy can be regarded as an end-organ effect of cumulative cardiovascular risk factors. Accelerate..

Regional neurodegeneration correlates with sleep-wake dysfunction after stroke

Elie Gottlieb, Natalia Egorova, Mohamed S Khlif, Wasim Khan, Emilio Werden, Matthew P Pase, Mark Howard, Amy Brodtmann

2020-09-01

Sleep-wake disruption is a key modifiable risk factor and sequela of stroke. The pathogenesis of poststroke sleep dysfunction is u..

Three-tissue compositional analysis reveals in-vivo microstructural heterogeneity of white matter hyperintensities following stroke

Wasim Khan, Natalia Egorova, Mohamed Salah Khlif, Remika Mito, Thijs Dhollander, Amy Brodtmann

2020-09-01

White matter hyperintensities (WMHs) are frequently observed on brain scans of older individuals and are associated with cognitive..

Pervasive White Matter Fiber Degeneration in Ischemic Stroke

Natalia Egorova, Thijs Dhollander, Mohamed Salah Khlif, Wasim Khan, Emilio Werden, Amy Brodtmann

2020-05-01

Background and Purpose- We examined if ischemic stroke is associated with white matter degeneration predominantly confined to the ..

Microstructural degeneration underlies executive dysfunction after stroke

Michele Veldsman, Emilio Werden, Natalia Egorova, Mohamed Salah Khlif, Amy Brodtmann

2020-02-04

<h4>ABSTRACT</h4> <h4>Objective</h4> Executive dysfunction affects 40% of stroke patients and is associated with poor quality of l..

Between placebo and nocebo: Response to control treatment is mediated by amygdala activity and connectivity

Natalia Egorova, Fabrizio Benedetti, Randy L Gollub, Jian Kong

2019-12-12

BACKGROUND: In experimental placebo and nocebo studies, neutral control treatments are often administered for comparison with acti..

Predicted Brain Age After Stroke

Natalia Egorova, Franziskus Liem, Vladimir Hachinski, Amy Brodtmann

2019-12-10

Aging is a known non-modifiable risk factor for stroke. Usually, this refers to chronological rather than biological age. Biologic..

Choroid plexus volume after stroke

Natalia Egorova, Elie Gottlieb, Mohamed Salah Khlif, Neil J Spratt, Amy Brodtmann

2019-12-01

BACKGROUND: Cerebrospinal fluid circulation is crucial for the functioning of the brain. Aging and brain pathologies such as Alzhe..

A Human Depression Circuit Derived From Focal Brain Lesions

Jaya L Padmanabhan, Danielle Cooke, Juho Joutsa, Shan H Siddiqi, Michael Ferguson, R Ryan Darby, Louis Soussand, Andreas Horn, Na Young Kim, Joel L Voss, Andrew M Naidech, Amy Brodtmann, Natalia Egorova, Sophia Gozzi, Thanh G Phan, Maurizio Corbetta, Jordan Grafman, Michael D Fox

2019-11-15

BACKGROUND: Focal brain lesions can lend insight into the causal neuroanatomical substrate of depression in the human brain. Howev..

A comparison of automated segmentation and manual tracing in estimating hippocampal volume in ischemic stroke and healthy control participants

Mohamed Salah Khlif, Natalia Egorova, Emilio Werden, Alberto Redolfi, Marina Boccardi, Charles S DeCarli, Evan Fletcher, Baljeet Singh, Qi Li, Laura Bird, Amy Brodtmann

2019-01-01

Manual quantification of the hippocampal atrophy state and rate is time consuming and prone to poor reproducibility, even when per..

A neural mechanism of direct and observational conditioning for placebo and nocebo responses

Yiheng Tu, Joel Park, Seppo P Ahlfors, Sheraz Khan, Natalia Egorova, Courtney Lang, Jin Cao, Jian Kong

2019-01-01

Classical theories suggest placebo analgesia and nocebo hyperalgesia are based on expectation and conditioned experience. Whereas ..

APOE epsilon 4 Carriers Show Delayed Recovery of Verbal Memory and Smaller Entorhinal Volume in the First Year After Ischemic Stroke

Emilio Werden, Mohamed Salah Khlif, Laura J Bird, Toby Cumming, Jennifer Bradshaw, Wasim Khan, Matthew Pase, Carolina Restrepo, Michele Veldsman, Natalia Egorova, Sheila K Patel, Elie Gottlieb, Amy Brodtmann

2019-01-01

BACKGROUND: The apolipoprotein E (APOE) gene ɛ4 allele is a risk factor for Alzheimer's disease and cardiovascular disease. Howeve..

Assessment of longitudinal hippocampal atrophy in the first year after ischemic stroke using automatic segmentation techniques

Mohamed Salah Khlif, Emilio Werden, Natalia Egorova, Marina Boccardi, Alberto Redolfi, Laura Bird, Amy Brodtmann

2019-01-01

We assessed first-year hippocampal atrophy in stroke patients and healthy controls using manual and automated segmentations: AdaBo..

In the face of pain: The choice of visual cues in pain conditioning matters

N Egorova, J Park, J Kong

2017-08-01

BACKGROUND: Visual cue conditioning is a valuable experimental paradigm to investigate placebo and nocebo effects in pain. However..