Wiring the retina for human vision - a single-cell behavioural approach

Grant number: DP180103393 | Funding period: 2018 - 2021

Completed

Abstract

This project aims to combine optical and behavioural methods to explore how colour information is channelled from individual cone photoreceptors through the living human retina, to the brain. By non-invasively stimulating either a single cell or specific arrangements of cells, the project aims to contribute fundamental knowledge about how the retina is wired to inform our exquisite sense of colour and spatial vision. This understanding has consequences across a range of disciplines, including artificial vision systems such as driverless cars, retinal disease, and the processing of information through neuronal connections in general.

Related publications (11)

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Direct measurement of pulse wave propagation in capillaries of the human retina

Phillip Bedggood, Andrew Metha

2021-09-15

With each contraction of the heart's left ventricle, a pulse pressure wave surges into the aorta and propagates throughout the vas..

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Towards distortion-free imaging of the eye

Phillip Bedggood, Andrew Metha

2021-06-10

The high power of the eye and optical components used to image it result in "static" distortion, remaining constant across acquire..

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Scaling the size of perimetric stimuli reduces variability and returns constant thresholds across the visual field

Phillip Bedggood, Selwyn Marc Prea, Yu Xiang George Kong, Algis J Vingrys

2020-10-01

The conventional stimulus for standard automated perimetry is fixed in size, giving elevated contrast thresholds and reduced test ..

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Are you sure? The relationship between response certainty and performance in visual detection using a perimetry-style task

Phillip Bedggood, Aiza Ahmad, Adam Chen, Rachael Lim, Sadiqa Maqsudi, Andrew Metha

2020-08-01

Conventional psychophysical methods ignore the degree of confidence associated with each response. We compared the psychometric fu..

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Recovering the appearance of the capillary blood column from under-sampled flow data

Phillip Bedggood, Andrew Metha

2020-08-01

The regular spacing of cells in capillary flow results in spurious cell trajectories if the sampling rate is too low. This makes i..

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Adaptive optics imaging of the retinal microvasculature

Phillip Bedggood, Andrew Metha

2019-12-03

The eye has long been recognised as the window to pathological processes occurring in the brain and other organs. By imaging the v..

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Imaging relative stasis of the blood column in human retinal capillaries

Phillip Bedggood, Andrew Metha

2019-11-01

Capillary flow largely consists of alternating red cells and plasma whose speed oscillates predictably with the cardiac cycle. Sup..

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Identifying transient flow phenomena in retinal capillaries

Phillip A Bedggood, Andrew Metha

2019-07-01

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The influence of perceptual stabilisation on perceptual grouping of temporally asynchronous stimuli

Adela SY Park, Phillip A Bedggood, Andrew B Metha, Andrew J Anderson

2019-07-01

Even during fixation, our eyes constantly make small, involuntary eye movements that cause the retinal image to be swept across ou..

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Mapping flow velocity in the human retinal capillary network with pixel intensity cross correlation

Phillip Bedggood, Andrew Metha

2019-06-25

We present a new method for determining cellular velocity in the smallest retinal vascular networks as visualized with adaptive op..

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Does Retinal Image Motion Arising From Smooth Pursuit Eye Movements Systematically Influence Temporal Perceptual Grouping?

Adela SY Park, Phillip A Bedggood, Andrew B Metha, Andrew J Anderson

2019-04-01

University of Melbourne Researchers