Nuclear architecture in a living cell facilitates navigation of the genome.

Grant number: DP180101387 | Funding period: 2018 - 2020

Completed

Abstract

This project aims to investigate the role of nuclear architecture in regulating genome function by development of a new microscopy method to quantify the diffusive route of fluorescent proteins in live cells. The anticipated outcomes of this project include an insight into how chromatin dynamics facilitate DNA target search and an analytical tool for cell biologists to probe how genomes work in their natural environment (the cell nucleus).

Related publications (11)

University of Melbourne Researchers