USING GENOMICS TO UNDERSTAND AND INTERRUPT TRANSMISSION OF SEXUALLY TRANSMITTED PATHOGENS IN AUSTRALIA
Grant number: 1147735 | Funding period: 2018 - 2020
Prevention and control of STIs in the 21st century requires timely, effective and high-resolution investigations which may be provided by genomic technologies. Building on existing datasets and expertise, we will provide a blueprint for genomics-based tracking of bacterial STIs in Australia, including the translation of this information to effect novel targeted public health actions, including screening, monitoring for outbreaks, and focused interventions to enhance control.
Related publications (7)
Nonclassical Pathogens as Causative Agents of Proctitis in Men who Have Sex With Men
Eric PF Chow, Darren Lee, Stephanie Bond, Christopher K Fairley, Kate Maddaford, Rebecca Wigan, Glenda Fehler, Sigrid A Lange, Vesna De Petra, Melanie Bissessor, Catriona S Bradshaw, Benjamin P Howden, Jane S Hocking, Deborah A Williamson, Marcus Y Chen
Background:This study aimed to identify enteric and sexually acquired rectal pathogens, other than chlamydia and gonorrhea, associ..
Reflex Detection of Ciprofloxacin Resistance in Neisseria gonorrhoeae by Use of the SpeeDx ResistancePlus GC Assay
Darren YJ Lee, Melinda M Ashcroft, Eric PF Chow, Michelle Sait, Vesna De Petra, Marlene Tschaepe, Sigrid Lange, George Taiaroa, Catriona S Bradshaw, David M Whiley, Christopher K Fairley, Benjamin P Howden, Marcus Y Chen, Shivani Pasricha, Deborah A Williamson
Resistance-guided therapy (RGT) for gonorrhea may reduce unnecessary use of broad-spectrum antibiotics. When reflexed from the Apt..
Co-circulation of Multidrug-resistant Shigella Among Men Who Have Sex With Men in Australia
Danielle J Ingle, Marion Easton, Mary Valcanis, Torsten Seemann, Jason C Kwong, Nicola Stephens, Glen P Carter, Anders Goncalves da Silva, James Adamopoulos, Sarah L Baines, Kathryn E Holt, Eric PF Chow, Christopher K Fairley, Marcus Y Chen, Martyn D Kirk, Benjamin P Howden, Deborah A Williamson
BACKGROUND: In urban Australia, the burden of shigellosis is either in returning travelers from shigellosis-endemic regions or in ..
Trends and Risk Factors for Antimicrobial-Resistant Neisseria gonorrhoeae, Melbourne, Australia, 2007 to 2018
Deborah A Williamson, Christopher K Fairley, Benjamin P Howden, Marcus Y Chen, Kerrie Stevens, Vesna De Petra, Ian Denham, Eric PF Chow
Antimicrobial resistance (AMR) in Neisseria gonorrhoeae is a major public health problem. Traditionally, AMR surveillance programs..
Bridging of Neisseria gonorrhoeae lineages across sexual networks in the HIV pre-exposure prophylaxis era
Deborah A Williamson, Eric PF Chow, Claire L Gorrie, Torsten Seemann, Danielle J Ingle, Nasra Higgins, Marion Easton, George Taiaroa, Yonatan H Grad, Jason C Kwong, Christopher K Fairley, Marcus Y Chen, Benjamin P Howden
Whole genome sequencing (WGS) has been used to investigate transmission of Neisseria gonorrhoeae, but to date, most studies have n..
Risk Factors for Asymptomatic Enteric Pathogen Detection Among Men Who Have Sex With Men
Deborah A Williamson, Eric PF Chow, Darren Lee, Kate Maddaford, Michelle Sait, Marion Easton, Danielle Ingle, Rebecca Wigan, Vesna De Petra, Benjamin P Howden, Christopher K Fairley, Marcus Y Chen
Improved knowledge of factors that promote outbreaks of enteric pathogens among men who have sex with men (MSM) could enable targe..