CARDIAC DYSFUNCTION IN ADVANCED LIVER DISEASE AND AFTER LIVER TRANSPLANTATION
Grant number: 1150874 | Funding period: 2018 - 2021
Heart disease is the leading cause of early death after liver transplantation (LT). The scarcity of donor organs means that LT is a limited and valuable resource. We propose screening for heart disease before LT by CT scanning of heart arteries and heart function on stress testing to improve detection of coronary heart disease (CHD). Follow-up CT scans will also assess if LT causes progression of CHD. These studies will aid in development of personalised treatment strategies to improve outcomes.
Related publications (4)
Relationship between QT interval prolongation and structural abnormalities in cirrhotic cardiomyopathy: A change in the current paradigm
Anoop N Koshy, Paul J Gow, Adam Testro, Andrew W Teh, Jefferson Ko, Han S Lim, Hui-Chen Han, Laurence Weinberg, Lisa B VanWagner, Omar Farouque
It is postulated that cardiac structural abnormalities observed in cirrhotic cardiomyopathy (CCM) contribute to the electrophysiol..
Effect of QT interval prolongation on cardiac arrest following liver transplantation and derivation of a risk index
Anoop N Koshy, Jefferson Ko, Omar Farouque, Shamil D Cooray, Hui-Chen Han, Benjamin Cailes, Paul J Gow, Laurence Weinberg, Adam Testro, Han S Lim, Andrew W Teh
Liver transplantation(LT) has a four-fold higher risk of periprocedural cardiac arrest and ventricular arrhythmias(CA/VA) compared..
Transcatheter aortic valve replacement in patients with a history of cancer: Periprocedural and long-term outcomes
Alexandra C Murphy, Anoop N Koshy, William Cameron, Mark Horrigan, Leighton Kearney, Belinda Yeo, Omar Farouque, Matias B Yudi
BACKGROUND: A history of cancer is incorporated into the surgical risk assessment of patients undergoing surgical aortic valve rep..