Targeting Monocyte Phagocytosis to Reduce Progression of Age Relate Macular Degeneration

Failure of autophagy–lysosomal pathways in rod photoreceptors causes the early retinal degeneration phenotype observed in Cln6 nclf mice

P von Eisenhart-Rothe, A Grubman, U Greferath, LJ Fothergill, AI Jobling, JA Phipps, AR White, EL Fletcher, KA Vessey

2018-10-01

PURPOSE. Vision loss caused by photoreceptor death represents one of the first symptoms in neuronal ceroid lipofuscinosis, a condi..

Nanosecond laser treatment for age-related macular degeneration does not induce focal vision loss or new vessel growth in the retina

KA Vessey, T Ho, AI Jobling, SA Mills, MX Tran, A Brandli, J Lam, RH Guymer, EL Fletcher

2018-02-01

PURPOSE. Subthreshold, nanosecond pulsed laser treatment shows promise as a treatment for age-related macular degeneration (AMD); ..

Reduced Phagocytosis as a novel pathogenic mechanism in AMD pathogenesis

Emily Caruso, Ben Gu, Erica L Fletcher, Xin Huang, Pavan Avula, Kirstan Anne Vessey, James Saville Wiley, Robyn H Guymer

2017-06-01

Loss of P2X7 receptor function increases the risk of age related macular degeneration: Investigation of human genetics and mouse models

Kirstan Anne Vessey, Ben J Gu, James S Wiley, Paul N Baird, Robyn H Guymer, Erica L Fletcher

2016-09-01