DISSECTING THE CONTRIBUTION OF IL-17-PRODUCING ΓΔ T CELLS IN THE PATHOGENESIS OF AIRWAY DISEASES

Grant number: 1147267 | Funding period: 2018 - 2020

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Abstract

Airway diseases such as severe steroid-refractory asthma and chronic obstructive pulmonary disease (COPD) are an enormous worldwide burden and have a huge public health impact. Approved drugs for these two diseases provide symptomatic relief but they do not halt the disease process, and curative therapy remains elusive. We have discovered a possible cause of chronic bronchitis, and using advanced techniques we are now probing for ways to turn this discovery into an effective treatment option.

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