Mechanisms of antifungal resistance in blackleg disease of canola
Grant number: LP170100548 | Funding period: 2018 - 2021
This project aims to determine how fungicide resistance evolves in the fungus Leptosphaeria maculans, the major pathogen of the oilseed crop canola. Global food production has become more reliant on the use of antifungal agents to protect crops, however these advances are now threatened by the emergence of drug-resistant microbes. The knowledge generated by this project will be used to reduce the risk of resistance evolving in populations of the blackleg fungus. This will have economic benefits through ensuring increased canola yields, while providing health and environmental benefits through minimisation of use of fungicides.
Related publications (5)
Epidemiology and management of blackleg of canola in response to changing farming practices in Australia
Angela P Van de Wouw, Stephen J Marcroft, Susan J Sprague, Jack L Scanlan, Peter A Vesk, Alexander Idnurm
The Australian canola industry was established in the 1970s and has expanded since that time, particularly in the last two decades..
The Third International Symposium on Fungal Stress - ISFUS
Alene Alder-Rangel, Alexander Idnurm, Alexandra C Brand, Alistair JP Brown, Anna Gorbushina, Christina M Kelliher, Claudia B Campos, David E Levin, Deborah Bell-Pedersen, Ekaterina Dadachova, Florian F Bauer, Geoffrey M Gadd, Gerhard H Braus, Gilberto UL Braga, Guilherme TP Brancini, Graeme M Walker, Irina Druzhinina, Istvan Pocsi, Jan Dijksterhuis, Jesus Aguirre
Stress is a normal part of life for fungi, which can survive in environments considered inhospitable or hostile for other organism..
A spontaneous mutation in DNA polymerase POL3 during in vitro passaging causes a hypermutator phenotype in Cryptococcus species
Kylie J Boyce, Chengjun Cao, Chaoyang Xue, Alexander Idnurm
Passaging of microbes in vitro can lead to the selection of microevolved derivatives with differing properties to their original p..