INVESTIGATING THE ANTIMICROBIAL ACTIVITY OF ZINC AT THE HOST-PNEUMOCOCCAL INTERFACE
Grant number: 1142695 | Funding period: 2018 - 2021
Streptococcus pneumoniae is a human-only bacterium that is responsible for killing more than one million people every year. This project will analyse how the human immune system fights this bacterium, and subsequently, how the bacteria manages to subvert these attacks and survive in the human host. This will provide crucial information for developing new drugs against this pathogen, in an attempt to combat the ever-increasing problem of antibiotic resistance.
Related publications (1)
Cadmium stress dictates central carbon flux and alters membrane composition in Streptococcus pneumoniae
Stephanie L Neville, Bart A Eijkelkamp, Amber Lothian, James C Paton, Blaine R Roberts, Jason W Rosch, Christopher A McDevitt
Metal ion homeostasis is essential for all forms of life. However, the breadth of intracellular impacts that arise upon dysregulat..