CHARACTERISATION AND DEVELOPMENT OF MAIT CELLS
Grant number: 1160333 | Funding period: 2019 - 2022
Completed
Abstract
MAIT cells are the most abundant T cell population in the human immune system, and have striking clinical potential for universal immunotherapy. Curiously however, MAIT cell numbers vary widely between individuals, so I seek to understand how they develop and decipher factors that control their function and numbers. This work will set the scene for future studies, and yield important clues about how best to target MAIT cells so they can be exploited as immunotherapy for diseases like cancer.