Protein Absorption and Kinetics in Critical Illness

Grant number: 1144496 | Funding period: 2018 - 2020

Completed

Abstract

This experienced & productive group plan to perform a number of interrelated studies in patients with critical illness the aim of which will be to ascertain protein absorption & kinetics, & the relationship between protein intake & muscle physiology. The goal is to lay the groundwork for an understanding of protein in the nutritional support of these patients which will help us to later establish the optimum amount & type of protein to improve muscle strength, functional outcomes & survival.

Related publications (2)

Increasing protein dose does not further augment muscle protein synthesis in critical illness: a randomized, controlled clinical trial

MJ Summers, IWK Kouw, IE Asser, R Louis, N Anand Devanand, T Arunachala Murthy, MP Plummer, AM Deane, E Raith, KM Lange, S Court-Kowalski, N Yadav, Y Chai, LJC van Loon, MJ Chapman, LAS Chapple

2026-05-01

RATIONALE: Critical illness impairs the muscle protein synthetic response to protein administration. Whether increased protein dos..

Muscle Protein Synthesis after Protein Administration in Critical Illness

LAS Chapple, IWK Kouw, MJ Summers, LM Weinel, S Gluck, E Raith, P Slobodian, S Soenen, AM Deane, LJC van Loon, MJ Chapman

2022-09-15

Rationale: Dietary protein may attenuate the muscle atrophy experienced by patients in the ICU, yet protein handling is poorly und..

University of Melbourne Researchers

Adam Deane