REBALANCING THE LEVELS OF CCL17 AND CCL22 TO IMPROVE RHEUMATOID ARTHRITIS

Autocrine IFN-I inhibits isocitrate dehydrogenase in the TCA cycle of LPS-stimulated macrophages

David P De Souza, Adrian Achuthan, Man KS Lee, Katrina J Binger, Ming-Chin Lee, Sophia Davidson, Dedreia L Tull, Malcolm J McConville, Andrew D Cook, Andrew J Murphy, John A Hamilton, Andrew J Fleetwood

2019-10-01

Macrophage activation in response to LPS is coupled to profound metabolic changes, typified by accumulation of the TCA cycle inter..