REGULATION OF GLYCEMIC CONTROL BY SECRETED MODULAR CALCIUM-BINDING PROTEIN 1

GIP receptor deletion in mice confers resistance to high-fat diet-induced obesity via alterations in energy expenditure and adipose tissue lipid metabolism.

Geke Aline Boer, Stacey N Keenan, Paula M Miotto, Jens Juul Holst, Matthew J Watt

2021-04-01

Glucose-dependent insulinotropic polypeptide (GIP) is best known as an incretin hormone that is secreted from K-cells of the proxi..

SMOC1 is a glucose-responsive hepatokine and therapeutic target for glycemic control

Magdalene K Montgomery, Jacqueline Bayliss, Camille Devereux, Ayenachew Bezawork-Geleta, David Roberts, Cheng Huang, Ralf B Schittenhelm, Andrew Ryan, Scott L Townley, Luke A Selth, Trevor J Biden, Gregory R Steinberg, Dorit Samocha-Bonet, Ruth CR Meex, Matthew J Watt

2020-09-02

Intertissue communication is a fundamental feature of metabolic regulation, and the liver is central to this process. We have iden..

The Liver as an Endocrine Organ-Linking NAFLD and Insulin Resistance

Matthew J Watt, Paula M Miotto, William De Nardo, Magdalene K Montgomery

2019-10-01

The liver is a dynamic organ that plays critical roles in many physiological processes, including the regulation of systemic gluco..