THE COMPLEMENT CASCADE, CORTICAL THINNING AND THE DEVELOPMENT OF PSYCHOSIS
Grant number: 1159674 | Funding period: 2019 - 2023
Schizophrenia is a complex disorder with devastating consequences to those that experience it. Despite over a century of research we are still not clear what biological factors influence the disorder. This research will investigate the role of a specific component of the immune system, called complement proteins, in the blood and brain of schizophrenia patients and how they impact patient outcomes. This research will improve our understanding of the biological factors involved in schizophrenia.
Related publications (1)
Investigation of peripheral complement factors across stages of psychosis
Liliana Laskaris, Andrew Zalesky, Cynthia Shannon Weickert, Maria A Di Biase, Gursharan Chana, Bernhard T Baune, Chad Bousman, Barnaby Nelson, Patrick McGorry, Ian Everall, Christos Pantelis, Vanessa Cropley
The complement cascade has been proposed to contribute to the pathogenesis of schizophrenia. However, it remains unclear whether p..