The Genomic Drivers Of High Risk Prostate Cancer

Abstract

Prostate cancer is now the most commonly diagnosed cancer but only 10% of men with it, will die from it. Our current ability to discriminate between cancers with an indolent course and those that are lethal is poor. This project will define the genetic changes associated with high risk disease and by linking with other large international studies generate a set of signature changes that can be used to screen the blood of early stage patients and identify those with high risk disease.