THE PRETEND TRIAL: A MIXED METHODS STUDY EVALUATING PREFERENCES, FEASIBILITY, AND COSTS OF PERFORMING SHAM SURGERY TRIALS INVOLVING MAJOR SURGICAL PROCEDURES
Grant number: 1163613 | Funding period: 2019 - 2021
Randomising patients to receive either an 'active' or a 'sham' (pretend) surgery and comparing the outcomes is the best way to test how effective a surgical procedure is. However, few orthopaedic surgeries have been tested in this way. This study aims to determine the feasibility of conducting a sham surgery trial in a major orthopaedic procedure by 1. identifying the conditions under which patients and surgeons would consider participating 2. Estimating how much it would cost.
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Placebo Surgery Controlled Trials Do They Achieve What They Set Out To Do? A Systematic Review
Samantha Bunzli, Emma Choong, Cade Shadbolt, Laura Wall, Elizabeth Nelson, Chris Schilling, Helen Wilding, L Stefan Lohmander, Zsolt J Balogh, Francesco Paolucci, Philip Clarke, Peter FM Choong, Michelle M Dowsey
OBJECTIVE: To explore whether placebo surgery controlled trials achieve what they set out to do by investigating discrepancy betwe..
Attitudes of patients and surgeons towards sham surgery trials: a protocol for a scoping review of attributes to inform a discrete choice experiment
Laura Wall, Madeleine Hinwood, Danielle Lang, Angela Smith, Samantha Bunzli, Philip Clarke, Peter FM Choong, Michelle M Dowsey, Francesco Paolucci
INTRODUCTION: In order to properly evaluate the efficacy of orthopaedic procedures, rigorous, randomised controlled sham surgery t..