ILLUMINATING GENOMIC DARK MATTER TO DEVELOP NEW INTERVENTIONS FOR PARASITES
Grant number: LP180101085 | Funding period: 2019 - 2024
Related publications (8)
High-quality reference genome for Clonorchis sinensis
Neil D Young, Andreas J Stroehlein, Liina Kinkar, Tao Wang, Woon-Mok Sohn, Bill CH Chang, Parwinder Kaur, David Weisz, Olga Dudchenko, Erez Lieberman Aiden, Pasi K Korhonen, Robin B Gasser
The Chinese liver fluke, Clonorchis sinensis, causes the disease clonorchiasis, affecting ~35 million people in regions of China, ..
Nanopore Sequencing Resolves Elusive Long Tandem-Repeat Regions in Mitochondrial Genomes
Liina Kinkar, Robin B Gasser, Bonnie L Webster, David Rollinson, D Timothy J Littlewood, Bill CH Chang, Andreas J Stroehlein, Pasi K Korhonen, Neil D Young
Long non-coding, tandem-repetitive regions in mitochondrial (mt) genomes of many metazoans have been notoriously difficult to char..
Diversity in the intrinsic apoptosis pathway of nematodes
Neil D Young, Tiffany J Harris, Marco Evangelista, Sharon Tran, Merridee A Wouters, Tatiana P Soares da Costa, Nadia J Kershaw, Robin B Gasser, Brian J Smith, Erinna F Lee, W Douglas Fairlie
Early studies of the free-living nematode C. elegans informed us how BCL-2-regulated apoptosis in humans is regulated. However, su..
First record of a tandem-repeat region within the mitochondrial genome ofClonorchis sinensisusing a long-read sequencing approach
Liina Kinkar, Neil D Young, Woon-Mok Sohn, Andreas J Stroehlein, Pasi K Korhonen, Robin B Gasser
BACKGROUND: Mitochondrial genomes provide useful genetic markers for systematic and population genetic studies of parasitic helmin..
A Targeted "Next-Generation" Sequencing-Informatic Approach to Define Genetic Diversity in Theileria orientalis Populations within Individual Cattle: Proof-of-Principle
Anson Koehler, Abdul Jabbar, Ross S Hall, Robin B Gasser
Oriental theileriosis is an economically important tickborne disease of bovines, caused by some members of the Theileria orientali..
Elucidating the molecular and developmental biology of parasitic nematodes: Moving to a multiomics paradigm
Guangxu Ma, Tao Wang, Pasi K Korhonen, Andreas Hofmann, Paul W Sternberg, Neil D Young, Robin B Gasser
In the past two decades, significant progress has been made in the sequencing, assembly, annotation and analyses of genomes and tr..