NEXT-GENERATION GENOMIC RESOURCES TO TACKLE PARASITIC DISEASES OF ANIMALS
Grant number: LP180101334 | Funding period: 2019 - 2022
The revolution in genomics provides unprecedented opportunities to tackle destructive parasitic diseases affecting billions of animals worldwide. Through a synergy of leading-edge technologies and a strong partnership with BGI International, this project aims to deliver major conceptual advances in the understanding of parasitism; an unparalleled skills-base in genomics and bioinformatics; innovative new molecular technologies; and new treatments and diagnostic tests as biotechnological outcomes. This leap forward in Australia will substantially enhance the global profile of parasitology research, training and employment opportunities for early career scientists, and improve access to intern..View full description
Related publications (7)
High-quality reference genome for Clonorchis sinensis
Neil D Young, Andreas J Stroehlein, Liina Kinkar, Tao Wang, Woon-Mok Sohn, Bill CH Chang, Parwinder Kaur, David Weisz, Olga Dudchenko, Erez Lieberman Aiden, Pasi K Korhonen, Robin B Gasser
The Chinese liver fluke, Clonorchis sinensis, causes the disease clonorchiasis, affecting ~35 million people in regions of China, ..
Nanopore Sequencing Resolves Elusive Long Tandem-Repeat Regions in Mitochondrial Genomes
Liina Kinkar, Robin B Gasser, Bonnie L Webster, David Rollinson, D Timothy J Littlewood, Bill CH Chang, Andreas J Stroehlein, Pasi K Korhonen, Neil D Young
Long non-coding, tandem-repetitive regions in mitochondrial (mt) genomes of many metazoans have been notoriously difficult to char..
Diversity in the intrinsic apoptosis pathway of nematodes
Neil D Young, Tiffany J Harris, Marco Evangelista, Sharon Tran, Merridee A Wouters, Tatiana P Soares da Costa, Nadia J Kershaw, Robin B Gasser, Brian J Smith, Erinna F Lee, W Douglas Fairlie
Early studies of the free-living nematode C. elegans informed us how BCL-2-regulated apoptosis in humans is regulated. However, su..
First record of a tandem-repeat region within the mitochondrial genome ofClonorchis sinensisusing a long-read sequencing approach
Liina Kinkar, Neil D Young, Woon-Mok Sohn, Andreas J Stroehlein, Pasi K Korhonen, Robin B Gasser
BACKGROUND: Mitochondrial genomes provide useful genetic markers for systematic and population genetic studies of parasitic helmin..
Elucidating the molecular and developmental biology of parasitic nematodes: Moving to a multiomics paradigm
Guangxu Ma, Tao Wang, Pasi K Korhonen, Andreas Hofmann, Paul W Sternberg, Neil D Young, Robin B Gasser
In the past two decades, significant progress has been made in the sequencing, assembly, annotation and analyses of genomes and tr..