CENTRE FOR TRANSLATIONAL BREAST CANCER RESEARCH (TRANSBCR): DELIVERING LABORATORY DISCOVERIES TO THE CLINIC

Dual Targeting of CDK4/6 and BCL2 Pathways Augments Tumor Response in Estrogen Receptor-Positive Breast Cancer.

James R Whittle, François Vaillant, Elliot Surgenor, Antonia N Policheni, Göknur Giner, Bianca D Capaldo, Huei-Rong Chen, He K Liu, Johanna F Dekkers, Norman Sachs, Hans Clevers, Andrew Fellowes, Thomas Green, Huiling Xu, Stephen B Fox, Marco J Herold, Gordon K Smyth, Daniel HD Gray, Jane E Visvader, Geoffrey J Lindeman

2020-08-01

PURPOSE: Although cyclin-dependent kinase 4 and 6 (CDK4/6) inhibitors significantly extend tumor response in patients with metasta..