Development of a Novel Drug Class for the Treatment of Plasmodium Falciparum Malaria
Grant number: 1171794 | Funding period: 2020 - 2022
Completed
Abstract
Recent gains made in malarial control are now threatened by the emergence of antimalarial drug resistance, which is causing up to 50% treatment failure. New drugs are needed that have novel mechanisms of action, are fast acting and show activity against all known resistant parasite strains. We have identified a class of compounds that fits these criteria and propose to develop them as drug leads.