USING PROTEIN STRUCTURE TO COMBAT ANTIMICROBIAL RESISTANCE

Grant number: 1174405 | Funding period: 2020 - 2021

Completed

Abstract

The development & spread of antimicrobial resistance poses significant risks to human health. Sequencing offers enormous potential to manage this but understanding how & which mutations lead to resistance is challenging. This program will use the effects of mutations on the structure & function of proteins to pre-emptively identify resistance mutations. This information will be used to improve diagnosis of what drugs a pathogen is resistant to & in the development of resistance-resistant drugs.

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