DEVELOPING NEW DIAGNOSTICS TO PREVENT STILLBIRTH

Circulating Growth Differentiation Factor 15 Is Increased Preceding Preeclampsia Diagnosis: Implications as a Disease Biomarker

Tess Cruickshank, Teresa M MacDonald, Susan P Walker, Emerson Keenan, Kirsten Dane, Anna Middleton, Valerie Kyritsis, Jenny Myers, Catherine Cluver, Roxanne Hastie, Lina Bergman, Damanpreet Garcha, Ping Cannon, Elizabeth Murray, Tuong-Vi Nguyen, Richard Hiscock, Natasha Pritchard, Natalie J Hannan, Stephen Tong, Tu'uhevaha J Kaitu'u-Lino

2021-08-17

Background We investigated the biomarker potential of growth differentiation factor 15 (GDF-15), a stress response protein highly ..

Circulating syndecan-1 is reduced in pregnancies with poor fetal growth and its secretion regulated by matrix metalloproteinases and the mitochondria

Damanpreet Garcha, Susan P Walker, Teresa M MacDonald, Jon Hyett, Jessica Jellins, Jenny Myers, Sebastian E Illanes, Jhy K Nien, Manuel Schepeler, Emerson Keenan, Carole-Anne Whigham, Ping Cannon, Elizabeth Murray, Tuong-Vi Nguyen, Manju Kandel, Joshua Masci, Ciara Murphy, Tess Cruickshank, Natasha Pritchard, Natalie J Hannan

2021-08-16

Fetal growth restriction is a leading cause of stillbirth that often remains undetected during pregnancy. Identifying novel biomar..

Circulating Tissue Factor Pathway Inhibitor (TFPI) is increased preceding preeclampsia diagnosis and in established preeclampsia

Teresa M MacDonald, Stephen Tong, Jenny Myers, Ping Cannon, Nguyen Tuong-Vi, Emerson Keenan, Elizabeth Murray, Alesia Harper, Natasha Pritchard, Natalie J Hannan, Kirsten M Dane, Anna L Middleton, Valerie P Kyritsis, Susan P Walker, Tu'uhevaha J Kaitu'u-Lino

2021-02-01

INTRODUCTION: Tissue Factor Pathway Inhibitor (TFPI) is a part of the extrinsic coagulation pathway, and highly expressed in the p..

Circulating mRNAs are differentially expressed in pregnancies with severe placental insufficiency and at high risk of stillbirth

Natalie J Hannan, Owen Stock, Rebecca Spencer, Clare Whitehead, Anna L David, Katie Groom, Scott Petersen, Amanda Henry, Joanne M Said, Sean Seeho, Stefan C Kane, Lavinia Gordon, Sally Beard, Kantaraja Chindera, Smita Karegodar, Richard Hiscock, Natasha Pritchard, Tu'uhevaha J Kaitu'u-Lino, Susan P Walker, Stephen Tong

2020-05-22

Background Fetuses affected by placental insufficiency do not receive adequate nutrients and oxygenation, become growth restricted..

Circulating SPINT1 is a biomarker of pregnancies with poor placental function and fetal growth restriction

Tu'uhevaha J Kaitu'u-Lino, Teresa M MacDonald, Ping Cannon, Nguyen Tuong-Vi, Richard J Hiscock, Nick Haan, Jenny E Myers, Roxanne Hastie, Kirsten M Dane, Anna L Middleton, Intissar Bittar, Amanda N Sferruzzi-Perri, Natasha Pritchard, Alesia Harper, Natalie J Hannan, Valerie Kyritsis, Nick Crinis, Lisa Hui, Susan P Walker, Stephen Tong

2020-05-15

Purpose To investigate the relationship between patient-reported outcome (PRO) questionnaire responses and time to late age-relate..