RECOGNITION OF PHOSPHOANTIGEN BY GAMMA-DELTA T CELLS
Grant number: 1184906 | Funding period: 2020 - 2024
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Abstract
Understanding how the immune system recognizes foreign pathogens is important, and guides us in the development of new immune therapeutics for diseases such as cancer. This study aims to understand how a specialized subset of immune T cells, known as gamma-delta T cells, recognizes and responds to a highly novel class of foreign antigens, termed phosphoantigens. Our proposal will set the scene for development of novel forms of cancer immunotherapy.