MECHANISMS AND BIOLOGICAL IMPACT OF DAPTOMYCIN RESISTANCE IN VRE

Grant number: 1185213 | Funding period: 2020 - 2023

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Abstract

Daptomycin is a last resort antibiotic used to treat vancomycin resistant Enterococcus faecium. If the use of daptomycin is lost due to widespread resistance, clinicians will be faced with the prospect of combatting a potentially untreatable hospital infection. This application will determine the prevalence of daptomycin resistance in Australia and define the mechanisms and consequences of this resistance. This knowledge will be critical for preserving this essential antibiotic.

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