ADULT STEM CELL-DERIVED ORGANOIDS: INNOVATIVE MODELS TO ELUCIDATE SIGNALLING MECHANISMS IN WNT-ADDICTED CANCERS

Investigating virus-host cell interactions: Comparative binding forces between hepatitis C virus-like particles and host cell receptors in 2D and 3D cell culture models

Simon Collett, Joseph Torresi, Linda Earnest Silveira, Vi Khanh Truong, Dale Christiansen, Bang M Tran, Elizabeth Vincan, Paul A Ramsland, Aaron Elbourne

2021-06-15

Cell cultures have been successfully used to study hepatitis C virus (HCV) for many years. However, most work has been done using ..

Captopril, a Renin-Angiotensin System Inhibitor, Attenuates Features of Tumor Invasion and Down-Regulates C-Myc Expression in a Mouse Model of Colorectal Cancer Liver Metastasis

Georgina E Riddiough, Theodora Fifis, Katrina A Walsh, Vijayaragavan Muralidharan, Christopher Christophi, Bang M Tran, Elizabeth Vincan, Marcos V Perini

2021-06-01

(1) Background: Recent clinical and experimental data suggests that the liver's regenerative response following partial hepatectom..

Targeting Wnt Signaling for the Treatment of Gastric Cancer

Sarah Koushyar, Arfon G Powell, Elizabeth Vincan, Toby J Phesse

2020-06-01

The Wnt signaling pathway is evolutionarily conserved, regulating both embryonic development and maintaining adult tissue homeosta..

The Hepatitis B Virus Pre-Core Protein p22 Activates Wnt Signaling

Manh Tran Bang, Dustin James Flanagan, Gregor Ebert, Nadia Warner, Tran Hoanh, Theodora Fifis, Georgios Kastrappis, Christopher Christophi, Marc Pellegrini, Joseph Torresi, Toby James Phesse, Elizabeth Vincan

2020-06-01

An emerging theme for Wnt-addicted cancers is that the pathway is regulated at multiple steps via various mechanisms. Infection wi..