THE PREVALENCE OF ALZHEIMER'S DISEASE PATHOLOGY AFTER TRAUMATIC BRAIN INJURY IN VETERANS AND CIVILIANS: A BIOMARKER STUDY OF BETA-AMYLOID AND TAU
Grant number: W81XWH-19-1-0746 | Funding period: 2019 - 2023
PUBLIC ABSTRACT Background: Some old research studies have suggested that people with brain injuries maybe 400% more likely to lose their brain function due to a dementia called Alzheimer’s disease (AD). Modern studies have yet to be able to confirm a direct link. Two modern brain scans called Amyloid-PET and Tau-PET can now measure directly the plaques in the brain caused by AD. In addition another modern brain scan 7T-MRI can also measure other brain abnormalities like bleeding, loss of brain cells, and micro-strokes. Specific Aims: (1) Measure plaques in the brain caused by AD using these modern PET brain scans in Vietnam Veterans and car accident victims. (2) Measure other brain injuries..View full description
Related publications (1)
β-Amyloid and Tau Imaging in Chronic Traumatic Brain Injury: A Cross-sectional Study.
Amelia J Hicks, Jennie L Ponsford, Gershon Spitz, Vincent Dore, Natasha Krishnadas, Caroline Roberts, Christopher C Rowe
BACKGROUND AND OBJECTIVES: Traumatic brain injury (TBI) has been promoted as a risk factor for Alzheimer disease (AD). There is ev..