DIAMONDS - Diagnosis and Management of Febrile Illness using RNA Personalised Molecular Signature Diagnosis
Grant number: 1195743 | Funding period: 2020 - 2025
We will develop and validate technologies to provide rapid diagnosis to patients presenting to primary care and hospitals on the basis of gene expression signatures in blood.
Related publications (6)
Long-Read RNA Sequencing Identifies Polyadenylation Elongation and Differential Transcript Usage of Host Transcripts During SARS-CoV-2 In Vitro Infection
Jessie J-Y Chang, Josie Gleeson, Daniel Rawlinson, Ricardo De Paoli-Iseppi, Chenxi Zhou, Francesca L Mordant, Sarah L Londrigan, Michael B Clark, Kanta Subbarao, Timothy P Stinear, Lachlan JM Coin, Miranda E Pitt
Better methods to interrogate host-pathogen interactions during Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) infec..
Phylodynamic Inference of Bacterial Outbreak Parameters Using Nanopore Sequencing
Eike Steinig, Sebastian Duchene, Izzard Aglua, Andrew Greenhill, Rebecca Ford, Mition Yoannes, Jan Jaworski, Jimmy Drekore, Bohu Urakoko, Harry Poka, Clive Wurr, Eri Ebos, David Nangen, Laurens Manning, Moses Laman, Cadhla Firth, Simon Smith, William Pomat, Steven YC Tong, Lachlan Coin
Nanopore sequencing and phylodynamic modeling have been used to reconstruct the transmission dynamics of viral epidemics, but thei..
Positive-unlabeled learning in bioinformatics and computational biology: a brief review
Fuyi Li, Shuangyu Dong, Andre Leier, Meiya Han, Xudong Guo, Jing Xu, Xiaoyu Wang, Shirui Pan, Cangzhi Jia, Yang Zhang, Geoffrey Webb, Lachlan JM Coin, Chen Li, Jiangning Song
Conventional supervised binary classification algorithms have been widely applied to address significant research questions using ..
Computational analysis and prediction of PE_PGRS proteins using machine learning
Fuyi Li, Xudong Guo, Dongxu Xiang, Miranda E Pitt, Arnold Bainomugisa, Lachlan JM Coin
Mycobacterium tuberculosis genome comprises approximately 10% of two families of poorly characterised genes due to their high GC c..
Porpoise: a new approach for accurate prediction of RNA pseudouridine sites
Fuyi Li, Xudong Guo, Peipei Jin, Jinxiang Chen, Dongxu Xiang, Jiangning Song, Lachlan JM Coin
Pseudouridine is a ubiquitous RNA modification type present in eukaryotes and prokaryotes, which plays a vital role in various bio..
Transcriptional and epi-transcriptional dynamics of SARS-CoV-2 during cellular infection
Jessie J-Y Chang, Daniel Rawlinson, Miranda E Pitt, George Taiaroa, Josie Gleeson, Chenxi Zhou, Francesca L Mordant, Ricardo De Paoli-Iseppi, Leon Caly, Damian FJ Purcell, Timothy P Stinear, Sarah L Londrigan, Michael B Clark, Deborah A Williamson, Kanta Subbarao, Lachlan JM Coin
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) uses subgenomic RNA (sgRNA) to produce viral proteins for replication..