Boosting the Immune System to Treat Diabetic Retinopathy.

Targeting RORγ to Boost Regulatory T cells and Ameliorate Diabetic Retinopathy in Mice

D Deliyanti, V Suphapimol, P Ang, A Jayasimhan, JL Wilkinson-Berka

2026-02-01

Diabetic retinopathy, a leading cause of blindness, features damage to the retinal vasculature, where T-cell–mediated inflammation..

Immunotherapy with low-dose IL-2 attenuates vascular injury in mice with diabetic and neovascular retinopathy by restoring the balance between Foxp3 Tregs and CD8 T cells

D Deliyanti, V Suphapimol, A Joglekar, A Jayasimhan, JL Wilkinson-Berka

2025-07-01

Aims/hypothesis: Diabetic retinopathy features damage to the retinal microvasculature that causes vessels to leak and proliferate ..

Overcoming Monocarboxylate Transporter 8 (MCT8)-Deficiency to Promote Human Oligodendrocyte Differentiation and Myelination

Jae Young Lee, Min Joung Kim, Devy Deliyanti, Michael F Azari, Fernando Rossello, Adam Costin, Georg Ramm, Edouard G Stanley, Andrew G Elefanty, Jennifer L Wilkinson-Berka, Steven Petratos

2017-11-01

Cell membrane thyroid hormone (TH) transport can be facilitated by the monocarboxylate transporter 8 (MCT8), encoded by the solute..