A MULTIPLE MODALITY APPROACH FOR TARGETING CHEMOTHERAPY-AND PARPI-RESISATNT OVARIAN CANCER

CX-5461 can destabilize replication forks in PARP inhibitor-resistant models of ovarian cancer

Jiachen Xuan, Richard B Pearson, Elaine Sanij

2020-09-02

Acquired drug resistance leads to poor clinical outcome in high grade serous ovarian cancer (HGSOC). We have demonstrated the effi..