Stem Cell-Derived Human Tissue Models for the Identification of Drugs to Treat COVID-19

Ancestral, Delta, and Omicron (BA.1) SARS-CoV-2 strains are dependent on serine proteases for entry throughout the human respiratory tract

MJ Gartner, LYY Lee, FL Mordant, R Suryadinata, J Chen, P Robinson, JM Polo, K Subbarao

2023-12-08

Background: The SARS-CoV-2 Omicron BA.1 variant emerged in late 2021 and became the globally dominant variant by January 2022. Aut..

Parallel use of human stem cell lung and heart models provide insights for SARS-CoV-2 treatment

R Rudraraju, MJ Gartner, JA Neil, ES Stout, J Chen, EJ Needham, M See, C Mackenzie-Kludas, LY Yang Lee, M Wang, H Pointer, K Karavendzas, D Abu-Bonsrah, D Drew, YB Yang Sun, JP Tan, G Sun, A Salavaty, N Charitakis, HT Nim

2023-06-13

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) primarily infects the respiratory tract, but pulmonary and cardiac co..