Healthy Lungs for Life: A Life Course Approach to Reduce COPD

Grant number: 1193993 | Funding period: 2021 - 2025

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Abstract

Chronic Obstructive Lung Disease (COPD) causes breathing distress, disability and premature death. I have shown that COPD mostly has its origins in childhood. This means we can now identify early life risk factors to prevent COPD or help us catch it early, to improve health. My 5-year vision is to reduce the dire burden of COPD by creating evidence to change guidelines and policy and facilitating the transfer of that knowledge to practice.

Related publications (4)

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Epigenomic variability is associated with age-specific naive CD4 T cell response to activation in infants and adolescents

Samira Imran, Melanie R Neeland, David JJ Martino, Stephen Peng, Jennifer Koplin, Shyamali C Dharmage, Mimi LK Tang, Susan Sawyer, Thanh Dang, Vicki McWilliam, Rachel L Peters, Susan Prescott, Kirsten P Perrett, Boris Novakovic, Richard Saffery

2023-03-01

Childhood is a critical period of immune development. During this time, naïve CD4 (nCD4) T cells undergo programmed cell different..

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Is antenatal or early-life vitamin D associated with eczema or food allergy in childhood? A systematic review

Rong Zeng, Yusi Li, Songying Shen, Xiu Qiu, Chia-Lun Chang, Jennifer JJ Koplin, Kirsten PP Perrett, Shyamali CC Dharmage, Caroline JJ Lodge, Adrian JJ Lowe

2023-01-17

OBJECTIVE: To summarise the associations between antenatal or early-life blood vitamin D and the development of eczema/food allerg..

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Early Childhood Pneumonia Is Associated with Reduced Lung Function and Asthma in First Nations Australian Children and Young Adults

Andrew J Collaro, Anne B Chang, Julie M Marchant, Mark D Chatfield, Don Vicendese, Tamara L Blake, Margaret S McElrea, Shyamali C Dharmage

2021-12-01

BACKGROUND: Some but not all previous studies report that pneumonia in children aged less than five years is associated with lower..

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Risk factors for chronic cough in adults: A systematic review and meta-analysis

Jingwen Zhang, Jennifer L Perret, Anne B Chang, Nur S Idrose, Dinh S Bui, Adrian J Lowe, Michael J Abramson, E Haydn Walters, Caroline J Lodge, Shyamali C Dharmage

2021-10-18

Despite the challenges of diagnosing and managing adult patients with chronic cough, a systematic synthesis of evidence on aetiolo..