Targeting vitamin-reactive T cells for enhanced immunity

Grant number: 1193745 | Funding period: 2021 - 2025



A specialised set of T cells called mucosal-associated invariant T (MAIT) cells react against bacteria and yeast, and reside at mucosal sites where the body's immune defences are often breached, e.g. respiratory tract and intestinal mucosa. This study seeks to define the molecular signals driving the function of MAIT cells, particularly during infections. This information may lead to methods tailored to manipulating MAIT cells therapeutically.

Related publications (6)

University of Melbourne Researchers