Understanding immunity to influenza B viruses for a rationally designed universal vaccine

Grant number: 1195698 | Funding period: 2021 - 2025

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Abstract

Influenza B viruses (IBV) circulate annually and are particularly prevalent and severe in children. However, IBV remain largely understudied. Our immune system provides protection against IBV via a variety of mechanisms. This study will characterize the immunity to IBV and dissect host-virus interactions which provide protection from IBV infection. This project will inform the rational design of novel vaccines eliciting universal immunity to IBV, with an ultimate goal of controlling IBV.

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