Reducing the Burden of Breast Cancer Through Precision Prevention, Targeted Treatment and Enhanced Survivorship

Grant number: 1195294 | Funding period: 2021 - 2025

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Abstract

Breast cancer affects 1 in 8 Australian women. Of all the cancers, breast cancer results in the largest number of years of healthy life lost from death and illness. My research will reduce this unacceptable burden of breast cancer for women and their families. Spanning prevention, through treatment to survivorship, it will facilitate reduced breast cancer incidence, more effective treatments and enhanced understanding of the effects of new treatments on ovarian function and fertility.

Related publications (5)

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Weight is More Informative than Body Mass Index for Predicting Postmenopausal Breast Cancer Risk: Prospective Family Study Cohort (ProF-SC)

Zhoufeng Ye, Shuai Li, Gillian S Dite, Tuong L Nguyen, Robert J MacInnis, Irene L Andrulis, Saundra S Buys, Mary B Daly, Esther M John, Allison W Kurian, Jeanine M Genkinger, Wendy K Chung, Kelly-Anne Phillips, Heather Thorne, Ingrid M Winship, Roger L Milne, Pierre-Antoine Dugue, Melissa C Southey, Graham G Giles, Mary Beth Terry

2022-03-01

UNLABELLED: We considered whether weight is more informative than body mass index (BMI) = weight/height2 when predicting breast ca..

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Recreational Physical Activity and Outcomes After Breast Cancer in Women at High Familial Risk

Rebecca D Kehm, Robert J MacInnis, Esther M John, Yuyan Liao, Allison W Kurian, Jeanine M Genkinger, Julia A Knight, Sarah Colonna, Wendy K Chung, Roger Milne, Nur Zeinomar, Gillian S Dite, Melissa C Southey, Graham G Giles, Sue-Anne Mclachlan, Kristen D Whitaker, Michael L Friedlander, Prue C Weideman, Gord Glendon, Stephanie Nesci

2021-12-08

BACKGROUND: Recreational physical activity (RPA) is associated with improved survival after breast cancer (BC) in average-risk wom..

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The value of clinical breast examination in a breast cancer surveillance program for women with germline BRCA1 or BRCA2 mutations

Tamara Hettipathirana, Courtney Macdonald, Jing Xie, Kate Moodie, Chris Michael, Kelly-Anne Phillips

2021-11-15

OBJECTIVE: To assess the sensitivity and specificity of clinical breast examination for detecting breast cancer in asymptomatic wo..

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Bilateral Salpingo-oophorectomy and Breast Cancer Risk for BRCA1 and BRCA2 Mutation Carriers: Assessing the Evidence

Ciara Conduit, Roger L Milne, Michael L Friedlander, Kelly-Anne Phillips

2021-11-01

Without preventive interventions, women with germline pathogenic variants in BRCA1 or BRCA2 have high lifetime risks for breast ca..

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Assessment of Ovarian Function in Phase 3 (Neo)adjuvant Breast Cancer Clinical Trials: A Systematic Evaluation.

Wanyuan Cui, Prudence A Francis, Sherene Loi, Martha Hickey, Catharyn Stern, Lumine Na, Ann H Partridge, Sibylle Loibl, Richard A Anderson, Karla J Hutt, Louise A Keogh, Kelly-Anne Phillips

2021-05-28

<h4>Background</h4>Loss of ovarian function is a recognized adverse effect of chemotherapy for breast cancer, and of great importa..