Improving Reproductive Health Through Infectious Diseases Research

Grant number: 1197951 | Funding period: 2021 - 2025

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Abstract

Infectious diseases that impact upon reproductive health remain a major problem worldwide. This proposal will examine human papillomavirus infection, the role of the human microbiota in a number of conditions (necrotising enterocolitis, bacterial vaginosis, and human papillomavirus infection), and antibiotic resistance in sexually transmitted infections. The knowledge generated will be used to improve diagnostics.

Related publications (11)

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gyrA Mutations in Mycoplasma Genitalium and Their Contribution to Moxifloxacin Failure: Time for the Next Generation of Resistance-guided Therapy

Gerald L Murray, Erica L Plummer, Kaveesha Bodiyabadu, Lenka A Vodstrcil, Jose L Huaman, Jennifer A Danielewski, Teck Phui Chua, Dorothy A Machalek, Suzanne Garland, Michelle Doyle, Emma L Sweeney, David M Whiley, Catriona S Bradshaw

2023-02-01

BACKGROUND: While single nucleotide polymorphisms (SNPs) in Mycoplasma genitalium parC contribute to fluoroquinolone treatment fai..

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IPVS policy statement on HPV nucleic acid testing guidance for those utilising/considering HPV as primary precancer screening: Quality assurance and quality control issues.

Suzanne M Garland, Thomas Iftner, Kate Cuschieri, Andreas M Kaufmann, Marc Arbyn, Silvia de Sanjose, Mario Poljak, Joakim Dillner, Elizabeth R Unger, null IPVS Policy Committee

2023-02-01

We advise that only clinically validated HPV assays which have fulfilled internationally accepted performance criteria be used for..

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The Urethral Microbiota of Men with and without Idiopathic Urethritis

Erica L Plummer, Larissa K Ratten, Lenka A Vodstrcil, Gerald L Murray, Jennifer A Danielewski, Christopher K Fairley, Suzanne M Garland, Eric PF Chow, Catriona S Bradshaw

2022-10-03

Nongonococcal urethritis (NGU) is a common genital tract syndrome in men, and up to 50% of cases are considered idiopathic, i.e., ..

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parC Variants in Mycoplasma genitalium: Trends over Time and Association with Moxifloxacin Failure

Gerald L Murray, Kaveesha Bodiyabadu, Lenka A Vodstrcil, Dorothy A Machalek, Jennifer Danielewski, Erica L Plummer, Suzanne M Garland, David M Whiley, Emma L Sweeney, Catriona S Bradshaw

2022-04-27

Prevalence, trends, and treatment outcome estimates were generated for parC variants in macrolide-resistant Mycoplasma genitalium...

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Impact of 16S rRNA Single Nucleotide Polymorphisms on Mycoplasma genitalium Organism Load with Doxycycline Treatment

Teck-Phui Chua, Jennifer Danielewski, Kaveesha Bodiyabadu, Catriona S Bradshaw, Dorothy A Machalek, Suzanne M Garland, Erica L Plummer, Lenka A Vodstrcil, Gerald L Murray

2022-04-14

Doxycycline targets the 16S rRNA and is widely used for the treatment of sexually transmitted infections. While it is not highly e..

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Human Papillomavirus Antibody Levels Following Vaccination or Natural Infection Among Young Men Who Have Sex With Men

Eric PF Chow, Christopher K Fairley, Huachun Zou, Rebecca Wigan, Suzanne M Garland, Alyssa M Cornall, Steph Atchison, Sepehr N Tabrizi, Marcus Y Chen

2022-02-05

BACKGROUND: Australia introduced a school-based gender-neutral human papillomavirus (HPV) vaccination program for girls and boys a..

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Real-world impact and effectiveness assessment of the quadrivalent HPV vaccine: a systematic review of study designs and data sources

Wei Wang, Smita Kothari, Marc Baay, Suzanne M Garland, Anna R Giuliano, Mari Nygard, Christine Velicer, Joseph Tota, Anushua Sinha, Jozica Skufca, Thomas Verstraeten, Karin Sundstrom

2021-12-10

INTRODUCTION: Vaccine effectiveness and impact studies are typically observational, generating evidence after vaccine launch in a ..

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Accuracy of Self-reported Human Papillomavirus Vaccination Status Among Gay and Bisexual Adolescent Males: Cross-sectional Study

Eric PF Chow, Christopher K Fairley, Rebecca Wigan, Jane S Hocking, Suzanne M Garland, Alyssa M Cornall, Sepehr N Tabrizi, Marcus Y Chen

2021-12-01

BACKGROUND: Men who have sex with men are a risk group for anal human papillomavirus (HPV) and anal cancer. Australia introduced a..

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The Effect of Exogenous Sex Steroids on the Vaginal Microbiota: A Systematic Review

Larissa K Ratten, Erica L Plummer, Catriona S Bradshaw, Christopher K Fairley, Gerald L Murray, Suzanne M Garland, Deborah Bateson, Gilda Tachedjian, Lindi Masson, Lenka A Vodstrcil

2021-11-12

BACKGROUND: Exogenous sex steroids within hormonal contraception and menopausal hormone therapy (MHT) have been used for family pl..

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A Prospective, Open-Label Pilot Study of Concurrent Male Partner Treatment for Bacterial Vaginosis

Erica L Plummer, Lenka A Vodstrcil, Michelle Doyle, Jennifer A Danielewski, Gerald L Murray, Glenda Fehler, Christopher K Fairley, Dieter M Bulach, Suzanne M Garland, Eric PF Chow, Jane S Hocking, Catriona S Bradshaw

2021-09-01

Up to 50% of women receiving first-line antibiotics for bacterial vaginosis (BV) experience recurrence within 12 weeks. Evidence s..

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Editorial: Immunology of HPV Infection and Vaccination: Progress and Challenges

Paul V Licciardi, Ian H Frazer, Suzanne M Garland, Kim Mulholland

2021-03-12