Enhancing control of enteric bacteria through pathogen genomics
Grant number: 1195210 | Funding period: 2021 - 2025
Bacteria part of the Enterobacteriaceae family are responsible for causing significant enteric disease in Australia and internationally. Compounding the public health threat posed by these enteric bacteria is the rise in antimicrobial resistance, which limits treatment options. This project has three complementary research objectives; 1) to investigate new control strategies; 2) to better understand outbreak dynamics and; 3) to explore how bacteria are causing new disease in humans.
Related publications (7)
Genomic Diversity of Campylobacter lari Group Isolates from Europe and Australia in a One Health Context
Michele Gourmelon, Amine M Boukerb, Nesrine Nabi, Sangeeta Banerji, Katrine G Joensen, Joelle Serghine, Alexandre Cormier, Francis Megraud, Philippe Lehours, Thomas Alter, Danielle J Ingle, Martyn D Kirk, Eva M Nielsen
Members of the Campylobacter lari group are causative agents of human gastroenteritis and are frequently found in shellfish, marin..
Characterisation of Treponema pallidum lineages within the contemporary syphilis outbreak in Australia: a genomic epidemiological analysis
Mona L Taouk, George Taiaroa, Shivani Pasricha, Sophie Herman, Eric PF Chow, Francesca Azzatto, Bowen Zhang, Cheryll M Sia, Sebastian Duchene, Alvin Lee, Nasra Higgins, Jacqueline Prestedge, Yi Wei Lee, Nicholas R Thomson, Bianca Graves, Ella Meumann, Manoji Gunathilake, Jane S Hocking, Catriona S Bradshaw, Mathew A Beale
BACKGROUND: The incidence of syphilis has increased markedly in the past decade in high-income countries, including Australia. To ..
Whole genome sequence analysis of Salmonella Typhi in Papua New Guinea reveals an established population of genotype 2.1.7 sensitive to antimicrobials
Zoe Anne Dyson, Elisheba Malau, Paul F Horwood, Rebecca Ford, Valentine Siba, Mition Yoannes, William Pomat, Megan Passey, Louise M Judd, Danielle J Ingle, Deborah A Williamson, Gordon Dougan, Andrew R Greenhill, Kathryn E Holt
BACKGROUND: Typhoid fever, a systemic infection caused by Salmonella enterica serovar Typhi, remains a considerable public health ..
Genomic diversity of antimicrobial resistance in non-typhoidal Salmonella in Victoria, Australia.
Cheryll M Sia, Sarah L Baines, Mary Valcanis, Darren YJ Lee, Anders Gonçalves da Silva, Susan A Ballard, Marion Easton, Torsten Seemann, Benjamin P Howden, Danielle J Ingle, Deborah A Williamson
Non-typhoidal Salmonella (NTS) is the second most common cause of foodborne bacterial gastroenteritis in Australia with antimicr..
Genomic Epidemiology and Antimicrobial Resistance Mechanisms of Imported Typhoid in Australia
Danielle J Ingle, Patiyan Andersson, Mary Valcanis, Mathilda Wilmot, Marion Easton, Courtney Lane, Jessica Barden, Anders Goncalves da Silva, Torsten Seemann, Kristy Horan, Susan A Ballard, Norelle L Sherry, Deborah A Williamson, Benjamin P Howden
Typhoid fever is an invasive bacterial disease of humans that disproportionately affects low- and middle-income countries. Antimic..
Evolutionary dynamics of multidrug resistant Salmonella enterica serovar 4,,12:i:- in Australia
Danielle J Ingle, Rebecca L Ambrose, Sarah L Baines, Sebastian Duchene, Anders Goncalves da Silva, Darren YJ Lee, Miriam Jones, Mary Valcanis, George Taiaroa, Susan A Ballard, Martyn D Kirk, Benjamin P Howden, Jaclyn S Pearson, Deborah A Williamson
Salmonella enterica serovar 4,,12:i:- (Salmonella 4,,12:i:-) is a monophasic variant of Salmonella Typhimurium that has emer..