Grant number: LE200100163 | Funding period: 2020 - 2022
Completed
Sara Hadjigol, Bansari A Shah, Neil M O'Brien-Simpson
2022-06-16
Over the past few decades, tremendous advances in the prevention, diagnosis, and treatment of cancer have taken place. However for..
Wenyi Li, Sara Hadjigol, Alicia Rasines Mazo, James Holden, Jason Lenzo, Steven J Shirbin, Anders Barlow, Sadegh Shabani, Tao Huang, Eric C Reynolds, Greg G Qiao, Neil M O'Brien-Simpson
2022-06-08
Antibiotic resistance in bacteria, especially Gram-positive bacteria like Staphylococcus aureus, is gaining considerable momentum ..
Thomas NG Handley, Wenyi Li, Nicholas G Welch, Neil M O'Brien-Simpson, Mohammed Akhter Hossain, John D Wade
2022-04-13
The day is rapidly approaching where current antibiotic therapies will no longer be effective due to the development of multi-drug..
Wenyi Li, Feng Lin, Andrew Hung, Anders Barlow, Marc-Antoine Sani, Rita Paolini, William Singleton, James Holden, Mohammed Akhter Hossain, Frances Separovic, Neil M O'Brien-Simpson, John D Wade
2022-02-01
Antimicrobial peptides (AMPs) are host defense peptides, and unlike conventional antibiotics, they possess potent broad spectrum a..
Bruce Lin, Andrew Hung, Rong Li, Anders Barlow, William Singleton, Tamara Matthyssen, Marc-Antoine D Sani, Mohammed Akhter Hossain, John Wade, Neil M O'Brien-Simpson, Wenyi Li
2022-01-24
The World Health Organisation has deemed several multi-drug resistant (MDR) nosocomial bacterial pathogens to be of significant th..
Tamara Matthyssen, Wenyi Li, James A Holden, Jason C Lenzo, Sara Hadjigol, Neil M O'Brien-Simpson
2022-01-10
Antimicrobial peptides (AMPs) are found in nearly all living organisms, show broad spectrum antibacterial activity, and can modula..
Zhe Sun, Wenyi Li, Jason C Lenzo, James A Holden, Michael J McCullough, Andrea J O'Connor, Neil M O'Brien-Simpson
2021-12-22
Vaccination is one of the most efficacious and cost-effective ways to protect people from infectious diseases and potentially canc..
Tetiana Hourani, James A Holden, Wenyi Li, Jason C Lenzo, Sara Hadjigol, Neil M O'Brien-Simpson
2021-12-20
The tumor microenvironment (TME) is known to have a strong influence on tumorigenesis, with various components being involved in t..
Bruce Lin, Rong Li, Thomas NG Handley, John D Wade, Wenyi Li, Neil M O'Brien-Simpson
2021-09-30
Oral dental infections are one of the most common diseases affecting humans, with caries and periodontal disease having the highes..
Wenyi Li, Frances Separovic, Neil M O'Brien-Simpson, John D Wade
2021-04-21
Antimicrobial resistance (AMR) is one of the greatest threats to human health that, by 2050, will lead to more deaths from bacteri..
Tracey Luu, Wenyi Li, Neil M O'Brien-Simpson, Yuning Hong
2021-03-25
Antimicrobial peptides (AMPs) are being intensively investigated as they are considered promising alternatives to antibiotics wher..
Da'san MM Jaradat, Nehaya Al-Karablieh, Basmah HM Zaarer, Wenyi Li, Khalil KY Saleh, Anas J Rasras, Saeid Abu-Romman, Neil M O'Brien-Simpson, John D Wade
2021-03-01
Increasing antibiotic resistance in Gram-negative bacteria has mandated the development of both novel antibiotics and alternative ..
Tao Huang, James A Holden, Eric C Reynolds, Daniel E Heath, Neil M O'Brien-Simpson, Andrea J O'Connor
2020-12-16
Antibiotic-resistant bacteria are a severe threat to human health. The World Health Organization's Global Antimicrobial Surveillan..
Nicholas G Welch, Wenyi Li, Mohammed Akhter Hossain, Frances Separovic, Neil M O'Brien-Simpson, John D Wade
2020-12-01
As we rapidly approach a post-antibiotic era in which multi-drug resistant bacteria are ever-pervasive, antimicrobial peptides (AM..
Xin Li, Tao Huang, Daniel E Heath, Neil M O'Brien-Simpson, Andrea J O'Connor
2020-11-01
Microbial colonization, infection, and biofilm formation are major complications in the use of implants and are the predominant ri..