Evaluation of new biomarkers of coagulation in high risk cardiovascular population
Grant number: 1151535 | Funding period: 2020 - 2021
Predicting the cardiovascular risk of an individual remains challenging despite the current advances and to date, there is no available laboratory testing that accurately reflects an individual’s clotting profile. This prospective study aims to address this with the use of global coagulation assay as a novel tool for individual cardiovascular risk prognostication and management, as well as demonstrate the compensatory mechanism between the different arms of Virchow's triad.
Related publications (6)
Global coagulation assays in patients with diabetes mellitus
Hui Yin Lim, Brandon Lui, Mark Tacey, Anna Kwok, Suresh Varadarajan, Geoffrey Donnan, Harshal Nandurkar, Prahlad Ho
BACKGROUND: There is significant heterogeneity in the incidence and severity of diabetes-associated vascular complications and the..
Global coagulation assays in healthy controls: are there compensatory mechanisms within the coagulation system?
Hui Yin Lim, Brandon Lui, Mark Tacey, Carly Selan, Geoffrey Donnan, Louise M Burrell, Harshal Nandurkar, Prahlad Ho
Global coagulation assays (GCAs) may provide a more comprehensive individual hemostatic profiling. We aim to evaluate GCAs (thromb..
Global Coagulation Assays in Transgender Women on Oral and Transdermal Estradiol Therapy
Hui Yin Lim, Shalem Y Leemaqz, Niloufar Torkamani, Mathis Grossmann, Jeffrey D Zajac, Harshal Nandurkar, Prahlad Ho, Ada S Cheung
Context The thrombotic effects of estradiol therapy in transgender women are unclear. Global coagulation assays (GCA) may be bette..