INVESTIGATING THE GENETIC CONTRIBUTION TO THE FOCAL EPILEPSIES

Evaluating risk to people with epilepsy during the COVID-19 pandemic: Preliminary findings from the COV-E study

Jennifer Thorpe, Samantha Ashby, Asma Hallab, Ding Ding, Maria Andraus, Patricia Dugan, Piero Perucca, Daniel Costello, Jacqueline A French, Terence J O'Brien, Chantal Depondt, Danielle M Andrade, Robin Sengupta, Norman Delanty, Nathalie Jette, Charles R Newton, Martin J Brodie, Orrin Devinsky, J Helen Cross, Josemir W Sander

2021-02-01

The COVID-19 pandemic has caused global anguish unparalleled in recent times. As cases rise, increased pressure on health services..

Genetic Contributions to Acquired Epilepsies

Piero Perucca, Ingrid E Scheffer

2021-01-01

Whether genetic factors contribute to acquired epilepsies has long been controversial. Supporters observe that, among individuals ..

Cardiorespiratory and autonomic function in epileptic seizures: A video-EEG monitoring study

Shobi Sivathamboo, Thomas N Constantino, Zhibin Chen, Paul B Sparks, Jeremy Goldin, Dennis Velakoulis, Nigel C Jones, Patrick Kwan, Vaughan G Macefield, Terence J O'Brien, Piero Perucca

2020-10-01

PURPOSE: Seizure-induced cardiorespiratory and autonomic dysfunction has long been recognized, and growing evidence points to its ..

Antiepileptic Drug Teratogenicity and De Novo Genetic Variation Load

Piero Perucca, Alison Anderson, Dana Jazayeri, Alison Hitchcock, Janet Graham, Marian Todaro, Torbjorn Tomson, Dina Battino, Emilio Perucca, Meritxell Martinez Ferri, Anne Rochtus, Lieven Lagae, Maria Paola Canevini, Elena Zambrelli, Ellen Campbell, Bobby PC Koeleman, Ingrid E Scheffer, Samuel F Berkovic, Patrick Kwan, Sanjay M Sisodiya

2020-04-15

OBJECTIVE: The mechanisms by which antiepileptic drugs (AEDs) cause birth defects (BDs) are unknown. Data suggest that AED-induced..